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Genome Integrity Discussion Group (3)

Genome Integrity Discussion Group

Monday, December 4, 2017, 1:30 PM - 4:30 PM

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York, USA

Presented By

Genome Integrity Discussion Group

The New York Academy of Sciences


The connection between cancer and genome integrity is widely appreciated. Importantly, the greater New York Metropolitan area is unparalleled in the concentration of world leading research on chromosome biology and function, as well as for research at the interface between chromosome integrity and the dynamics of malignancy. The Genome Integrity Discussion Group capitalize on this concentration of excellence, providing a forum for interaction between basic- and clinically-oriented research groups working in these fields. These meetings not only facilitate synergy between labs, but also provide a context in which previously unappreciated complementarities can be revealed.

In that spirit, the talks will cover a broad range of areas, including, but not limited to the DNA damage response and cancer predisposition, DNA replication, transcription, chromatin modification, recombination, cell cycle control, telomeres, chromosome segregation, epigenetic states, as well as the emergence of new technologies relevant to research in genome integrity. Although a primary focus is upon basic mechanisms and processes, these areas are pertinent to cancer and myriad human disease states, and it is expected that this will be reflected in the substance of our discussions. At each of the meetings, two early career scientists (students or postdocs) are selected to present data.
Genome Integrity Discussion Group meetings are organized under the leadership of Scott Keeney (Memorial Sloan Kettering Cancer Center), Susan Smith (NYU Langone Medical Center), and Lorraine Symington (Columbia University Irving Medical Center).

Call for Student/Postdoc Presentation Abstracts: Deadline November 3, 2017

Two abstracts will be selected for short talks by students/postdocs. Please submit abstracts in CSHL format with file name via email to Professor Keeney at by November 3, 2017, for consideration.


Nonmember Academia, Faculty, etc.
Nonmember Corporate, Other
Nonmember Not for Profit
Nonmember Student, Undergrad, Grad, Fellow
Member Student, Post-Doc, Fellow


Genome Integrity Discussion Group (3)
Scott Keeney, PhD, Memorial Sloan Kettering Cancer Center
Genome Integrity Discussion Group (3)
Susan Smith, PhD, NYU Langone Medical Center
Genome Integrity Discussion Group (3)
Lorraine Symington, PhD, Columbia University Irving Medical Center
Genome Integrity Discussion Group (3)
Sonya Dougal, PhD, The New York Academy of Sciences


December 04, 2017

1:00 PM

Registration Opens

1:30 PM

Welcome and Introductory Remarks


Sonya Dougal, PhD
The New York Academy of Sciences
Scott Keeney, PhD
Memorial Sloan Kettering Cancer Center
1:40 PM

Phosphorylation-mediated clearance of amyloid-like assemblies in meiosis


Luke E. Berchowitz, PhD
Columbia University Irving Medical Center
2:10 PM

Mechanisms of Pol ε function revealed by modeling cancer-associated mutations in yeast


Xiaolan Zhao, PhD
Memorial Sloan Kettering Cancer Center
2:40 PM

Rad51 filaments are required for DNA damage-induced chromosomal mobility


Michael Smith, PhD
Columbia University Irving Medical Center (Rothstein Lab)
2:55 PM

Coffee Break

3:25 PM

CST counters resection at double-strand breaks


Zachary Mirman
The Rockefeller University (de Lange lab)
3:40 PM

Cytoplasmic chromatin triggers inflammation in senescence and cancer


Shelley Berger, PhD
University of Pennsylvania
4:10 PM

Type III CRISPR-Cas: Dissecting a Multi-Pronged Attack One Molecule at A Time


Shixin Liu, PhD
The Rockefeller University
4:40 PM

Networking Reception

5:30 PM


To view full attendee list, you must first register for the event, then log in to the Academy website. This list is provided for the personal, noncommercial and informational use only of event attendees, in a manner that is consistent with the New York Academy of Sciences’ mission, goals and activities.
  • Columbia University

  • Columbia University Irving Medical Center

  • Columbia University Medical Center

  • Genomic Vision

  • Long Island University, A&M Schwartz College of Pharmacy

  • Memorial Sloan Kettering Cancer Center

  • Memorial Sloan-Kettering Cancer Center

  • Millburn High School

  • Nature Publishing Group

  • New York University

  • NYU Langone Medical Center

  • NYU School of Medicine

  • The Columbia University School of Medicine

  • The Gerstner Sloan-Kettering Graduate School

  • The Icahn School of Medicine at Mount Sinai

  • The New York Academy of Sciences

  • The Rockefeller University

  • The Rockerfeller University

  • University of Pennsylvania

  • Weill Cornell Graduate School of Medical Sciences

  • Weill Cornell Medicine

  • Yale University

  • Yale University School of Medicine