Genome Integrity Discussion Group
Monday, October 2, 2017, 1:30 PM - 4:30 PM
The New York Academy of Sciences
The connection between cancer and genome integrity is widely appreciated. Importantly, the greater New York Metropolitan area is unparalleled in the concentration of world leading research on chromosome biology and function, as well as for research at the interface between chromosome integrity and the dynamics of malignancy. The Genome Integrity Discussion Group capitalize on this concentration of excellence, providing a forum for interaction between basic- and clinically-oriented research groups working in these fields. These meetings not only facilitate synergy between labs, but also provide a context in which previously unappreciated complementarities can be revealed.
In that spirit, the talks will cover a broad range of areas, including, but not limited to the DNA damage response and cancer predisposition, DNA replication, transcription, chromatin modification, recombination, cell cycle control, telomeres, chromosome segregation, epigenetic states, as well as the emergence of new technologies relevant to research in genome integrity. Although a primary focus is upon basic mechanisms and processes, these areas are pertinent to cancer and myriad human disease states, and it is expected that this will be reflected in the substance of our discussions. At each of the meetings, two early career scientists (students or postdocs) are selected to present data.
Genome Integrity Discussion Group meetings are organized under the leadership of Scott Keeney (Memorial Sloan Kettering Cancer Center), Susan Smith (NYU Langone Medical Center), and Lorraine Symington (Columbia University Irving Medical Center).
Call for Student/Postdoc Presentation Abstracts: Deadline September 8, 2017
Two abstracts will be selected for short talks by students/postdocs. Please submit abstracts in CSHL format with file name NYAS.name.doc via email to Professor Keeney at email@example.com by September 8, 2017, for consideration.
October 02, 2017
Welcome and Introductory Remarks
A Mechanism for Preventing DNA Replication Fork Collapse Under Replication Stress
Replication Fork Cleavage Drives Genomic Instability in BRCA-Deficient Cells
The Condensin Complex is a Mechanochemical Motor that Translocates Along DNA
The Mouse Shu Complex SWS1-SWSAP1 is Essential for Meiotic Recombination
How DNA Repair and Meiotic Progression are Coordinated in Budding Yeast
The Sister Chromatid Cohesion Cycle