Pediatric Cancer: Expediting Basic Research to Clinical Discovery (4)

Sohn Conference: Accelerating Translation of Pediatric Cancer Research

Monday, February 26, 2018 - Wednesday, February 28, 2018

The Royal Society, London, 6-9 Carlton House Terrace, London, GBR

Presented By

The Sohn Conference Foundation

The New York Academy of Sciences

 

Pediatric cancer is the leading cause of death by disease past infancy among children in the United States and Europe. Despite prevailing increases in overall survival rates, it continues to be one of the most challenging diseases to treat. Our basic understanding of pediatric cancer biology has improved, but high rates of relapse remain; and 20% of pediatric cancer patients do not respond to therapy, ultimately dying from their disease. We now understand that childhood cancers are genetically distinct from their adult counterparts, and that current treatments developed for adults are particularly harsh on growing children, causing severe side effects. Thus, there is a critical need to refine established therapeutic approaches for this vulnerable population to improve treatment for patients around the world.

This 2.5-day international conference will advance the dialogue from the first meeting presented jointly by the Sohn Conference Foundation and the New York Academy of Sciences in 2016, the Sohn Conference: Pediatric Cancer in a Post-genomic World. Leading researchers, clinicians, pediatric cancer advocates, and industry and governmental stakeholders from around the globe will reconvene, this time in London, England, to discuss strategies to help bridge the gap between basic research discoveries and treatments for pediatric and adolescent cancer patients. The aim will be to provide a platform for these leaders from different countries and continents to share promising new findings, identify best practices, and develop a unified approach. Conference speakers will present emerging basic and clinical cutting edge research in pediatric cancers on topics including somatic and germline alterations, genomics and epigenomics, opportunities and challenges in immunotherapy, developmental biology, biology of tumor progression and relapse, technologies for non-invasive disease monitoring, biological determinants of survival, and strategies challenges in clinical trial design and drug development.

Call for Abstracts

Abstract submissions are invited for a poster session. For complete submission instructions, please visit our online portal. The deadline for abstract submission is December 4, 2017.

Call for Early Career Investigator and Underrepresented Minority Travel Fellowship Applications

Applications are invited from qualified early career investigators and early career investigators from underrepresented minorities. For detailed information on eligibility and application instructions, please visit our online portal. The deadline for submission is December 4, 2017.

Registration

Member
By 01/15/2018
$205
After 01/15/2018
$240
Onsite
$275
Nonmember Academia, Faculty, etc.
By 01/15/2018
$255
After 01/15/2018
$290
Onsite
$330
Nonmember Corporate, Other
By 01/15/2018
$360
After 01/15/2018
$420
Onsite
$470
Nonmember Not for Profit
By 01/15/2018
$255
After 01/15/2018
$290
Onsite
$330
Nonmember Student, Undergrad, Grad, Fellow
By 01/15/2018
$140
After 01/15/2018
$170
Onsite
$200
Member Student, Post-Doc, Fellow
By 01/15/2018
$105
After 01/15/2018
$135
Onsite
$185

Presented by

The Sohn Conference Foundation supports innovative initiatives that promote its mission to treat and cure pediatric cancer.  Toward this goal, the Foundation seeks to embolden elite scientists researching pediatric cancers to collaborate across institutions and, with this Conference, across nations, to further research toward cures.  This Conference is also a meaningful reflection of the Foundation’s unique philanthropic model: the Foundation raises funds by convening leading investment professionals to share their best ideas and fundraise for the cause of pediatric cancer research.  It is therefore the Foundation’s privilege to partner with the New York Academy of Sciences to convene the world’s scientific leaders who will change the course of treating pediatric cancer, ultimately, saving more children from cancer and treatment side-effects.

Monday

February 26, 2018

1:10 PM

Registration

1:30 PM

Introduction and Welcome Remarks

Speakers

Piers Butler
The Sohn Foundation London
Melanie Brickman Borchard, PhD, MSc
The New York Academy of Sciences
1:40 PM

Day 1 Keynote Address

Speaker

Richard Gilbertson, MD, PhD
Cancer Research UK Cambridge Institute and University of Cambridge, United Kingdom

Session I: Inherited Predisposition to Childhood Cancers

2:20 PM

Title to Be Announced

Speaker

David Malkin, MD, FRCP(C), FAAP
The Hospital for Sick Children, Canada
2:45 PM

Title to Be Announced

Speaker

Nazneen Rahman, MD, PhD
The Institute of Cancer Research, United Kingdom
3:10 PM

Networking Coffee Break

Session II: Somatic Alterations in Pediatric Cancers: Genomics and Epigenomics

3:40 PM

Discovering New Therapeutic Targets in Pediatric Cancers with Integrative Genomics

Speaker

Kimberly Stegmaier, MD
Dana-Farber Cancer Institute, Harvard Medical School, and Boston Children's Hospital, United States
4:05 PM

Title to Be Announced

Speaker

Andrew Kung, MD, PhD
Memorial Sloan Kettering Cancer Center, United States
4:30 PM

Title to Be Announced

Speaker

Stefan Pfister, MD
Heidelberg University Hospital and German Cancer Research Center (DKFZ), Germany
4:55 PM

Closing Remarks

5:05 PM

Day 1 Ends

Tuesday

February 27, 2018

9:00 AM

Networking Breakfast, Poster Set Up

Session III: Opportunities and Challenges in Immunotherapy for the Treatment of Pediatric Cancers

9:30 AM

Title to Be Announced

Speaker

John Anderson, PhD
University College London Institute of Child Health, United Kingdom
9:55 AM

Immunogenomic Approaches to Childhood Cancers

Speaker

John Maris, MD
The Children’s Hospital of Philadelphia and the Perelman School of Medicine, University of Pennsylvania, United States
10:20 AM

Title to Be Announced

Speaker

Uri Tabori, MD
The Hospital for Sick Children, Canada
10:45 AM

Networking Coffee Break

Session IV: Incorporating Developmental Biology into Our Understanding of Pediatric Cancers

11:15 AM

Title to Be Announced

Speaker

Louis Chesler, PHD, MD, FRCPCH
The Royal Marsden and The Institute of Cancer Research, United Kingdom
11:40 AM

Title to Be Announced

Speaker

Scott Armstrong, MD, PhD
Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, and Broad Institute of MIT and Harvard
12:05 PM

Networking Lunch and Poster Viewing

Session V: Hot Topic Talks from Submitted Abstracts

1:20 PM

Selected from Submitted Abstracts

1:35 PM

Selected from Submitted Abstracts

Session VI: Emerging Biology of Tumor Progression and Relapse

1:50 PM

Stress-mediated Translational Control of Sarcoma Metastasis

Speaker

Poul Sorensen, MD, PhD
British Columbia Cancer Research Centre and University of British Columbia, Vancouver, Canada
2:15 PM

Speaker to Be Announced

2:40 PM

Speaker to Be Announced

3:05 PM

Day 2 Closing Remarks

3:15 PM

Networking Reception and Poster Session

5:00 PM

Day 2 Ends

Wednesday

February 28, 2018

9:00 AM

Networking Breakfast

9:25 AM

Day 3 Keynote Address:

Speaker

Mignon Lee-Cheun Loh, MD
University of California, San Francisco, United States

Session VII: Hot Topic Talks from Submitted Abstracts

10:05 AM

Selected from Submitted Abstracts

10:20 AM

Selected from Submitted Abstracts

10:35 AM

Networking Coffee Break

Session VIII: Emerging Technologies in Non-invasive Disease Monitoring

11:05 AM

Title to Be Announced

Speaker

Lee Helman, MD
Children’s Hospital of Los Angeles and the Norris Comprehensive Cancer Center, University of Southern California, United States
11:30 AM

Title to Be Announced

Speaker

Kathy Pritchard-Jones, BM BCh, PhD, FRCPCH
Great Ormond Street Institute of Child Health, University College London, United Kingdom
11:55 AM

Title to Be Announced

Speaker

Gudrun Schleiermacher, MD, PhD
Institut Curie, Paris, France
12:20 PM - 1:35 PM

Networking Lunch

Early Career Investigator and Underrepresented Minority Mentoring Lunch

For Graduate Students, Post-doctoral Fellows, and Junior Faculty

Session IX: Biological Determinants and Risk Factors of Survivorship in Pediatric Cancers

1:35 PM

Speaker to Be Announced

2:00 PM

Speaker to Be Announced

2:25 PM

Networking Coffee Break

Session X: Strategies and Challenges in Clinical Trial Design and Drug Development

2:55 PM

Title to Be Announced

Speaker

Gilles Vassal, MD, PhD
Gustave Roussy Institute, Villejuif, France
3:20 PM

Title to Be Announced

Speaker

Yael P. Mossé, MD
Children's Hospital of Philadelphia
3:45 PM

Speaker to Be Announced

4:10 PM

Panel Discussion: Accelerating Drug Development

4:55 PM

Day 3 Closing Remarks

5:00 PM

Conference Adjourns