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Alzheimer’s Disease Therapeutics: Alternatives to Amyloid

Available via

WEBINAR

Alzheimer’s Disease Therapeutics: Alternatives to Amyloid

Tuesday, December 11, 2018, 8:30 AM - 6:00 PM

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York

Presented By

The New York Academy of Sciences

The Brain and Behavior Discussion Group

 

For years, the Alzheimer’s research community has been focused on amyloid as the key to curing this devastating disease.  However, there are currently only four drugs approved to treat the symptoms of Alzheimer’s disease, and no new therapies have been approved in the last 15 years.  Moreover, multiple clinical trials have recently failed, including several Phase III trials that targeted amyloid with antibodies.  As a result, there is burgeoning interest in identifying alternative drug targets: over half of ongoing preclinical research in Alzheimer’s disease now focuses on pathways other than amyloid and tau.

This one-day symposium will highlight emerging mechanisms driving Alzheimer's disease — including mitochondrial factors, the vascular system, infections, and autophagy — as well as discuss strategies to identify new therapeutic targets.

Registration

Member
$60
Nonmember Academia, Faculty, etc.
$105
Nonmember Corporate, Other
$160
Nonmember Not for Profit
$105
Nonmember Student, Undergrad, Grad, Fellow
$70
Member Student, Post-Doc, Fellow
$25
Member
$30
Nonmember Academia, Faculty, etc.
$65
Nonmember Corporate, Other
$85
Nonmember Not for Profit
$65
Nonmember Student, Undergrad, Grad, Fellow
$45
Member Student, Post-Doc, Fellow
$15
Deadline:
0
days
left

Scientific Organizing Committee

Howard Fillit, MD,  Alzheimer's Drug Discovery Foundation
Howard Fillit, MD,
Alzheimer's Drug Discovery Foundation
Nell Rebowe,   Anavex Life Sciences
Nell Rebowe,
Anavex Life Sciences
Rudolph Tanzi, PhD,  Harvard Medical School
Rudolph Tanzi, PhD,
Harvard Medical School
George Zavoico, PhD,  B. Riley FBR
George Zavoico, PhD,
B. Riley FBR
Sara Donnelly, PhD,  The New York Academy of Sciences
Sara Donnelly, PhD,
The New York Academy of Sciences
Sonya Dougal, PhD,  The New York Academy of Sciences
Sonya Dougal, PhD,
The New York Academy of Sciences
Amanda Sadacca, PhD,  The New York Academy of Sciences
Amanda Sadacca, PhD,
The New York Academy of Sciences

Speakers

Ana Maria Cuervo, MD, PhD,  Albert Einstein College of Medicine**
Ana Maria Cuervo, MD, PhD,
Albert Einstein College of Medicine**
Howard Fillit, MD,  Alzheimer's Drug Discovery Foundation
Howard Fillit, MD,
Alzheimer's Drug Discovery Foundation
Paula Grammas, PhD,  University of Rhode Island
Paula Grammas, PhD,
University of Rhode Island
Jacob Hooker, PhD,  Harvard Medical School
Jacob Hooker, PhD,
Harvard Medical School
Xavier Langlois
Xavier Langlois, PhD,
Abbvie
Christopher Missling
Christopher Missling, PhD,
Anavex Life Sciences
Robert Moir, PhD,  Harvard Medical School
Robert Moir, PhD,
Harvard Medical School
Rudolph Tanzi, PhD,  Harvard Medical School
Rudolph Tanzi, PhD,
Harvard Medical School
Eugenia Trushina, PhD,  Mayo Clinic
Eugenia Trushina, PhD,
Mayo Clinic


** Not Participating in the Webinar

Tuesday

December 11, 2018

8:30 AM

Breakfast and Registration

9:00 AM

Introduction and Welcome Remarks

Speakers

Amanda Sadacca, PhD
The New York Academy of Sciences
9:15 AM

Overview of the Current State of Alzheimer’s Disease Therapeutics

Speaker

Howard Fillit, MD
Alzheimer’s Drug Discovery Foundation
9:30 AM

Alzheimer's Disease: The Role of Genes, Glia and Germs

Speaker

Rudolph Tanzi, PhD
Harvard University
10:00 AM

HDAC Dysregulation Assessed by PET Imaging in Alzheimer's Disease

Speaker

Jacob Hooker, PhD
Harvard Medical School
10:30 AM

Networking Coffee Break

11:00 AM

Mitochondria-Targeted Therapeutics for Alzheimer’s Disease

Speaker

Eugenia Trushina, PhD
Mayo Clinic
11:30 AM

Precision Medicine Approach for Treating Neurological Diseases via Sigma-1 Receptor Activation

Speaker

Christopher Missling, PhD
Anavex Life Sciences
12:00 PM

Blood-Derived Plasminogen Drives Brain Inflammation and Plaque Deposition in a Mouse Model of Alzheimer’s Disease

Speaker

Sarah Baker
The Rockefeller University
12:05 PM

Clinical Evaluation of Allogeneic Longeveron Mesenchymal Stem Cells for Mild Alzheimer’s Disease

Speaker

Joshua Hare, MD
Longeveron LLC
12:10 PM

Genetic Rescue of Mitochondrial Calcium Efflux in Alzheimer’s Disease Preserves Mitochondrial Function and Protects Against Cognitive Decline and Neuropathology

Speaker

Pooja Jadiya, PhD
Temple University
12:15 PM

Networking Lunch

1:30 PM

Targeting Vascular Activation: A New Therapeutic Approach to Alzheimer's Disease

Speaker

Paula Grammas, PhD
University of Rhode Island
2:00 PM

Tau Immunotherapy: Finding the Right Antibody for the Right Tau Species

Speaker

Xavier Langlois, PhD
AbbVie
2:30 PM

The Role of Autophagy in Alzheimer’s Disease

Speaker

Ana Maria Cuervo, MD, PhD **
Albert Einstein College of Medicine (Not participating in Webinar **)
3:00 PM

Networking Coffee Break

3:30 PM

The Antimicrobial Protection Hypothesis of Alzheimer’s Disease

Speaker

Robert Moir, PhD
Harvard Medical School
4:00 PM

Panel Discussion: Identifying Therapeutic Strategies to Combat Alzheimer’s Disease

Speaker

Moderator: Howard Fillit, MD
Alzheimer's Drug Discovery Foundation
4:40 PM

Closing Remarks

Speaker

Howard Fillit, MD
Alzheimer's Drug Discovery Foundation
4:45 PM

Poster Session and Networking Reception

5:30 PM

Presentation of F1000 Poster Prizes

5:45 PM

Adjourn

To view full attendee list, you must first register for the event, then log in to the Academy website. This list is provided for the personal, noncommercial and informational use only of event attendees, in a manner that is consistent with the New York Academy of Sciences’ mission, goals and activities.
  • Aadi Bioscience

  • Abbvie

  • Albert Einstein College of Medicine

  • Allergan

  • Alzheimer's Drug Discovery Foundation

  • Anavex Life Sciences Corp.

  • Asdera

  • B Riley FBR

  • BAM Consulting LLC

  • Biogen

  • Biomedical Research Institute of New Jersey

  • Century Innovations

  • Cerecin, Inc.

  • CNS Research Solutions LLC

  • CNS-ExecutiveSearch

  • Cold Spring Harbor Laboratory

  • Columbia University

  • Columbia University Graduate School of Arts and Sciences

  • Columbia University Irving Medical Center

  • Drew University

  • Duke University

  • F. Hoffmann-La Roche

  • Fox Chase Chemical Diversity Center

  • H. Lundbeck A/S

  • Harvard Medical School

  • Hunter College, CUNY

  • INmune Bio

  • Johnson & Johnson

  • Longeveron

  • Longeveron LLC

  • Massachusetts General Hospital and Harvard Medical School

  • Mayo Clinic

  • MerciaPharma

  • Merck & Co., Inc.

  • Mount Sinai Medical Center

  • New Jersey City University

  • New York University

  • New York University College of Dentistry

  • New York University Medical Center

  • Northwell Health, Inc.

  • Norton Klein Hug Sabin & Maddens MD PC

  • NYS Inst for Basic Research

  • PATH

  • Pepsico

  • Pfizer Centers for Therapeutic Innovation

  • Pfizer Inc

  • Pfizer Ventures

  • Pleasantville Friends of STEM,Inc.

  • Regeneron Pharmaceuticals, Inc

  • Ryan Institute for Neuroscience

  • Scientific American

  • Temple University School of Medicine

  • The Albert Einstein College of Medicine

  • The Icahn School of Medicine at Mount Sinai

  • The Rockefeller University

  • Trillium Medical Ventures LLC

  • UBIQUITOX

  • Uniformed Services University of the Health Sciences

  • University of Connecticut Health Center

  • University of Hartford

  • Valence Life Sciences, LLC

  • Wayne State University

  • Weill Cornell Medicine

  • West Virginia University