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WEBINAR
New Therapeutic Strategies to Combat Antibacterial Resistance
Tuesday, October 23, 2018, 9:00 AM - 6:00 PM EDT
The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York
Antibiotics are cornerstones of modern medicine, essential for treating patients across the spectrum of disease from routine skin infections to surgical procedures to protection for vulnerable patients receiving chemotherapy. The rise of multidrug resistance at an alarming rate constitutes a major threat to human health. According to the Centers for Disease Control and Prevention, each year in the U.S. alone, at least 2 million people become infected with bacteria that are resistant to antibiotics and 23,000 people die annually as a direct result of these infections. This symposium will focus on the current challenges that basic and translational researchers are facing to fight antimicrobial resistance, as well as offering perspectives on emerging therapeutic strategies to address this global health threat.
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Tuesday
October 23, 2018
Registration and Breakfast
Introduction and Welcome Remarks
Speakers
Keynote Address: Clinical Perspective on the Future of the Antibacterial Resistance Landscape
Speaker
Session 1: Leveraging Existing Therapies against New Targets
Bacterial Chemical Genomics: A Path of Ceased Resistance
Speaker
Networking Coffee Break
Predictive Guidelines for Compound Accumulation Lead to New Broad-Spectrum Antibiotics
Speaker
Kinetic and Molecular Determinants of Antibiotic Permeation Barriers
Speaker
Networking Lunch and Poster Viewing
Session 2: Innovative Approaches to Develop Novel Therapies
Predatory Bdellovibrio: Opportunities and Challenges as Anti-Pathogen Agents
Speaker
Conversion of Staphylococcal Pathogenicity Islands to CRISPR-Cas9-Based Antibacterial Drones
Speaker
Systems Chemical Biology Approach to Antibiotic Discovery
Speaker
Networking Coffee Break
Speaker
Session 3: Exploiting Host-Pathogen Interactions to Develop New Therapeutics
New Chemistry at the Bacterial Cell Surface: Targeting Virulence and Host-Pathogen Interactions
Speaker
Repurposing FDA-Approved Drugs to Sensitize MDR Pathogens to Innate Immune Clearance
Speaker
Microbiota-Mediated Defense against Intestinal Infection
Speaker
Closing Remarks
Speaker