
Available via
WEBINAR
Cancer Metabolism and Signaling
Thursday, May 24, 2018
The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York
There has been a resurgence of interest in understanding how metabolic pathways are altered in cancer and how these alterations can be exploited for therapeutic gain. Many of the signaling pathways that drive tumorigenesis directly regulate metabolic pathways that support cell growth. Increasingly, metabolites themselves are recognized to play important roles regulating tumor initiation and progression. Beyond providing the building blocks for cell proliferation, metabolites can directly influence stress response pathways, chromatin modifications and gene expression that collectively drive tumor development. This meeting will bring experts together to discuss the intersection between cancer cell signaling and metabolism and explore how cancer cells exploit cellular signaling and metabolic pathways to support malignant growth.
Registration
Organizers
Event Sponsors
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Cancer Discussion Group Lead Supporter
Cancer Discussion Group Supporter
Thursday
May 24, 2018
Breakfast and Registration
Introduction and Welcome Remarks
Speakers
Session 1: Metabolic Drivers of Cancer
Metabolic Transitions in Cancer: Regulation by Cell-Extrinsic Cues
Speaker
AMPK: Cancer Fighter, Cancer Supporter
Speaker
Uncovering Metabolic Bottlenecks in Lung Cancer
Speaker
Networking Coffee Break
Metabolic Symbioses in the Hypoxia Tumor Microenvironment
Speaker
Session 2: Data Blitz Presentations
Acquired Resistance to IDH Inhibition through Trans or Cis Dimer-Interface Mutations
Speaker
Identification of Nutrient Auxotrophies of Blood Cancers
Speaker
LDH-A Expression Impacts on the Tumor Microenvironment via HIF-Signaling
Speaker
Networking Lunch and Poster Session
Session 3: Targeting Metabolism in Tumors
Metabolic Compensation to Ablated Mitochondrial Folate Use in Triple-Negative Breast Cancer: Discovering Metabolic Vulnerabilities
Speaker
Acetyl-CoA Metabolism and Tumorigenesis
Speaker
The Metabolic Regulation of Cancer Progression
Speaker
Cysteine Metabolism in Pancreatic Cancer
Speaker
Networking Coffee Break
Keynote Lecture: PI 3-Kinase and Cancer Metabolism
Speaker
Closing Remarks and F1000 Poster Prize Presentation
Speaker