Cancer Metabolism and Signaling

Available via

WEBINAR

Cancer Metabolism and Signaling

Thursday, May 24, 2018

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York

Presented By

Cancer Discussion Group

The New York Academy of Sciences

 

There has been a resurgence of interest in understanding how metabolic pathways are altered in cancer and how these alterations can be exploited for therapeutic gain. Many of the signaling pathways that drive tumorigenesis directly regulate metabolic pathways that support cell growth. Increasingly, metabolites themselves are recognized to play important roles regulating tumor initiation and progression. Beyond providing the building blocks for cell proliferation, metabolites can directly influence stress response pathways, chromatin modifications and gene expression that collectively drive tumor development. This meeting will bring experts together to discuss the intersection between cancer cell signaling and metabolism and explore how cancer cells exploit cellular signaling and metabolic pathways to support malignant growth.

Registration

Member
$60
Nonmember Academia, Faculty, etc.
$105
Nonmember Corporate, Other
$160
Nonmember Not for Profit
$105
Nonmember Student, Undergrad, Grad, Fellow
$70
Member Student, Post-Doc, Fellow
$25
Member
$30
Nonmember Academia, Faculty, etc.
$65
Nonmember Corporate, Other
$85
Nonmember Not for Profit
$65
Nonmember Student, Undergrad, Grad, Fellow
$45
Member Student, Post-Doc, Fellow
$15
Deadline:
0
days
left

Speakers

Cancer Metabolism and Signaling
Thales Papagiannakopoulos, PhD, NYU School of Medicine
Cancer Metabolism and Signaling
Kathryn Wellen, PhD, University of Pennsylvania Perelman School of Medicine
Cancer Metabolism and Signaling
M. Celeste Simon, PhD, University of Pennsylvania Perelman School of Medicine
Cancer Metabolism and Signaling
Lewis C. Cantley, PhD, Weill Cornell Medical College
Cancer Metabolism and Signaling
Heather Christofk, PhD, University of California, Los Angeles
Cancer Metabolism and Signaling
Steven Gross, PhD, Weill Cornell Medical Center
Cancer Metabolism and Signaling
Sean Morrison, PhD, UT Southwestern Medical Center
Cancer Metabolism and Signaling
Reuben J. Shaw, PhD, The Salk Institute for Biological Studies
Cancer Metabolism and Signaling
Kenneth P. Olive, PhD, Columbia University Irving Cancer Center

Bronze

Agilent




Thursday

May 24, 2018

8:30 AM

Breakfast and Registration

9:00 AM

Introduction and Welcome Remarks

Speakers

Sonya Dougal, PhD
The New York Academy of Sciences
Lydia Finley, PhD
Memorial Sloan Kettering Cancer Center

Session 1: Metabolic Drivers of Cancer

Session Chairperson
Lydia Finley, PhD
9:15 AM

Metabolic Transitions in Cancer: Regulation by Cell-Extrinsic Cues

Speaker

Heather Christofk, PhD
University of California, Los Angeles
9:45 AM

AMPK: Cancer Fighter, Cancer Supporter

Speaker

Reuben J. Shaw, PhD
The Salk Institute for Biological Studies
10:15 AM

Uncovering Metabolic Bottlenecks in Lung Cancer

Speaker

Thales Papagiannakopoulos, PhD
New York University School of Medicine
10:45 AM

Networking Coffee Break

11:15 AM

Metabolic Symbioses in the Hypoxia Tumor Microenvironment

Speaker

M. Celeste Simon, PhD
University of Pennsylvania Perelman School of Medicine

Session 2: Data Blitz Presentations

Session Chairperson
Lydia Finley, PhD
11:45 AM

Acquired Resistance to IDH Inhibition through Trans or Cis Dimer-Interface Mutations

Speaker

Andrew M. Intlekofer, MD, PhD
Memorial Sloan Kettering Cancer Center
11:50 AM

Identification of Nutrient Auxotrophies of Blood Cancers

Speaker

Javier Garcia-Bermudez, PhD
The Rockefeller University
11:55 AM

LDH-A Expression Impacts on the Tumor Microenvironment via HIF-Signaling

Speaker

Inna Serganova, PhD
Memorial Sloan Kettering Cancer Center
12:00 PM

Networking Lunch and Poster Session

Session 3: Targeting Metabolism in Tumors

Session Chairperson
Costas Lyssiotis, PhD
1:30 PM

Metabolic Compensation to Ablated Mitochondrial Folate Use in Triple-Negative Breast Cancer: Discovering Metabolic Vulnerabilities

Speaker

Steven Gross, PhD
Weill Cornell Medical Center
2:00 PM

Acetyl-CoA Metabolism and Tumorigenesis

Speaker

Kathryn Wellen, PhD
University of Pennsylvania Perelman School of Medicine
2:30 PM

Metabolic Regulation of Stem Cell Function and Tumorigenesis

Speaker

Sean Morrison, PhD
UT Southwestern Medical Center
3:00 PM

Cysteine Metabolism in Pancreatic Cancer

Speaker

Kenneth P. Olive, PhD
Columbia University Irving Medical Center
3:30 PM

Networking Coffee Break

4:00 PM

Keynote Lecture: PI 3-Kinase and Cancer Metabolism

Speaker

Lewis C. Cantley, PhD
Weill Cornell Medical College
4:45 PM

Closing Remarks and F1000 Poster Prize Presentation

Speaker

Costas Lyssiotis, PhD
University of Michigan Medical School
5:00 PM

Networking Reception

6:00 PM

Adjourn