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Frontiers in Cancer Immunotherapy

Available via

WEBINAR

Frontiers in Cancer Immunotherapy

Thursday, April 26, 2018 - Friday, April 27, 2018

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York

Presented By

Cancer Discussion Group

The New York Academy of Sciences

 

The recent FDA approval of a gene therapy for leukemia treatment marks a new frontier in medical innovation for the field of cancer immunotherapy. This 2-day scientific symposium will explore cutting-edge findings in basic science, translational research, and clinical studies to improve immunotherapeutic approaches. Plenary speakers active in the fields of cancer biology, immunology, and cancer immunotherapy will present on an array of topics, including: new mechanistic perspectives from basic and preclinical research, results from early phase clinical trials of combination therapies, the durability of treatment responses to CAR-T cell therapies, and managing the known toxicity of effective immunotherapies in clinical trials.

This symposium will feature a Career Exploration Roundtable presented in collaboration with Science Alliance. Targeting graduate students and postdoctoral fellows, this panel will feature senior postdocs and early-career scientists from industry and academia. Participants who are interested in attending this breakfast must register to attend the full Frontiers in Cancer Immunotherapy conference. Registrants will then receive a follow-up email that includes a link to register for the Career Exploration breakfast.

Registration

Member
By 03/09/2018
$175
After 03/09/2018
$200
Onsite
$250
Nonmember Academia, Faculty, etc.
By 03/09/2018
$250
After 03/09/2018
$300
Onsite
$375
Nonmember Corporate, Other
By 03/09/2018
$350
After 03/09/2018
$400
Onsite
$475
Nonmember Not for Profit
By 03/09/2018
$250
After 03/09/2018
$300
Onsite
$375
Nonmember Student, Undergrad, Grad, Fellow
By 03/09/2018
$175
After 03/09/2018
$200
Onsite
$350
Member Student, Post-Doc, Fellow
By 03/09/2018
$150
After 03/09/2018
$175
Onsite
$225
Member
$60
Nonmember Academia, Faculty, etc.
$130
Nonmember Corporate, Other
$170
Nonmember Not for Profit
$130
Nonmember Student, Undergrad, Grad, Fellow
$90
Member Student, Post-Doc, Fellow
$30
Member
$30
Nonmember Academia, Faculty, etc.
$65
Nonmember Corporate, Other
$85
Nonmember Not for Profit
$65
Nonmember Student, Undergrad, Grad, Fellow
$45
Member Student, Post-Doc, Fellow
$15
Member
$30
Nonmember Academia, Faculty, etc.
$65
Nonmember Corporate, Other
$85
Nonmember Not for Profit
$65
Nonmember Student, Undergrad, Grad, Fellow
$45
Member Student, Post-Doc, Fellow
$15
Deadline:
0
days
left

Organizers

George Zavoico, PhD, B. Riley FBR
George Zavoico, PhD, B. Riley FBR
Chris Boshoff, MD, PhD, Pfizer
Chris Boshoff, MD, PhD, Pfizer
Sridhar Ramaswamy, MD, Tesaro
Sridhar Ramaswamy, MD, Tesaro
Renier Brentjens, MD, PhD, Memorial Sloan Kettering Cancer Center
Renier Brentjens, MD, PhD, Memorial Sloan Kettering Cancer Center
Sara Donnelly, PhD, The New York Academy of Sciences
Sara Donnelly, PhD, The New York Academy of Sciences
Sonya Dougal, PhD, The New York Academy of Sciences
Sonya Dougal, PhD, The New York Academy of Sciences

Keynote Speakers

Miriam Merad, MD, PhD, Icahn School of Medicine at Mount Sinai
Miriam Merad, MD, PhD, Icahn School of Medicine at Mount Sinai
Jeffrey V. Ravetch, MD, PhD, The Rockefeller University
Jeffrey V. Ravetch, MD, PhD, The Rockefeller University

Speakers

Brian Ruffell, PhD,  Moffitt Cancer Center
Brian Ruffell, PhD, Moffitt Cancer Center
Dale L. Greiner PhD, University of Massachusetts Medical School
Dale L. Greiner PhD, University of Massachusetts Medical School
Marcela V. Maus, MD PhD, Harvard Medical School​
Marcela V. Maus, MD PhD, Harvard Medical School​
Marco Davila, MD, PhD,  Moffitt Cancer Center
Marco Davila, MD, PhD, Moffitt Cancer Center
Prasad S. Adusumilli, MD, Memorial Sloan Kettering Cancer Center
Prasad S. Adusumilli, MD, Memorial Sloan Kettering Cancer Center
Rong Fan, PhD, Yale University
Rong Fan, PhD, Yale University
Hans Klingemann, MD, PhD, NantKwest
Hans Klingemann, MD, PhD, NantKwest
Timothy Chan, MD, PhD, Memorial Sloan Kettering Cancer Center
Timothy Chan, MD, PhD, Memorial Sloan Kettering Cancer Center
David Spencer, PhD, Bellicum Pharmaceuticals
David Spencer, PhD, Bellicum Pharmaceuticals
Noah Palm, PhD, Yale University School of Medicine
Noah Palm, PhD, Yale University School of Medicine
Paolo Fiorina, MD, PhD, Harvard Medical School
Paolo Fiorina, MD, PhD, Harvard Medical School
Christopher Klebanoff, MD, Memorial Sloan Kettering Cancer Center
Christopher Klebanoff, MD, Memorial Sloan Kettering Cancer Center
David Jenkins, PhD, Tesaro
David Jenkins, PhD, Tesaro
Jennifer Wargo, MD, MD Anderson Cancer Center
Jennifer Wargo, MD, MD Anderson Cancer Center
Maria Fardis, PhD, MBA, Iovance Biotherapeutics
Maria Fardis, PhD, MBA, Iovance Biotherapeutics
Rachel Humphrey, MD,CytomX Therapeutics
Rachel Humphrey, MD,CytomX Therapeutics
Priti Hegde, PhD, Genentech
Priti Hegde, PhD, Genentech
Jane Gross, PhD, Aptevo Therapeutics
Jane Gross, PhD, Aptevo Therapeutics
James W. Hodge, PhD, MBA, National Cancer Institute
James W. Hodge, PhD, MBA, National Cancer Institute

Sponsors

The Cancer Discussion Group is Proudly Supported by:

This event is supported by medical education grants from Prometheus Laboratories, Inc and Abbvie.
 
Additional Support provided by
BioLife Solutions

Promotional Partners

American Association for Cancer Research (AACR)

Cancer Research Institute

Damon Runyon Cancer Research Foundation

Ludwig Institute for Cancer Research

Thursday

April 26, 2018

8:30 AM

Breakfast and Registration

9:00 AM

Introduction and Welcome Remarks

Speakers

Sonya Dougal, PhD
The New York Academy of Sciences
Renier Brentjens, MD, PhD
Memorial Sloan Kettering Cancer Center
9:15 AM

Combining Immune CheckPoint Blockers with Targeted Therapies

Speaker

Chris Boshoff, MD, PhD
Pfizer

Session 1: Innovative Tools for Immunotherapy

Session Chairperson
Renier Brentjens, MD, PhD, Memorial Sloan Kettering Cancer Center
9:45 AM

Current State of Humanized Mouse Models in Cancer Immunotherapy

Speaker

Dale Greiner, PhD
University of Massachusetts Medical School
10:15 AM

Single-Cell Integrative Analysis of CAR-T Cell Activation States

Speaker

Rong Fan, PhD
Yale University
10:45 AM

Insights into Modes of Action and Resistance to Checkpoint Inhibitors in Cancer

Speaker

Priti Hegde, PhD
Genentech
11:15 AM

Networking Coffee Break

Session 2: Mechanistic Perspectives driving the Next Generation of Immunotherapeutics

Session Chairperson
Dale L Greiner PhD, University of Massachusetts Medical School
11:45 AM

The Next Evolution of CD19-targeted CAR T Cells

Speaker

Marco Davila, MD, PhD
Moffitt Cancer Center
12:15 PM

CAR T-Cell Therapy for Solid Tumors

Speaker

Prasad Adusumilli, MD
Memorial Sloan Kettering Cancer Center
12:45 PM

T-Cell Therapy 2.0: Building the Next Generation of Adoptive Cancer Immunotherapies

Speaker

Christopher Klebanoff, MD
Memorial Sloan Kettering Cancer Center
1:15 PM

Networking Lunch and Poster Viewing

Session 3: Alternative Checkpoints and Cellular Therapies

Session Chairperson
Chris Boshoff, MD, PhD, Pfizer
2:30 PM

Developing Tumor Infiltrating Lymphocytes for the Treatment of Cancer

Speaker

Maria Fardis, PhD, MBA
Iovance Biotherapeutics
3:00 PM

Building on PD-1: new combinations to enhance therapeutic activity

Speaker

David Jenkins, PhD
Tesaro
3:30 PM

Networking Coffee Break

4:00 PM

Engineered, Off the Shelf, NK Cell Lines for Targeted Cancer Immunotherapy

Speaker

Hans Klingemann, MD, PhD
NantKwest
4:30 PM

TIM-3 Regulates Dendritic Cell Function and Anti-Tumor Immunity

Speaker

Brian Ruffell, PhD
Moffitt Cancer Center
5:00 PM

Keynote Lecture- Next Generation Immunotherapeutics for Cancer: Coupling Innate and Adaptive Immunity

Speaker

Jeffrey Ravetch, MD, PhD
The Rockefeller University
5:45 PM

Networking Reception and Poster Viewing

6:30 PM

Day 1 Adjourns

Friday

April 27, 2018

8:00 AM

Breakfast and Registration

8:00 AM

Early Career Development Mentoring Breakfast

Location: *Registration required. Limited to Graduate Students and Postdocs

Speakers

Michael Arensman, PhD
Pfizer
Renier Brentjens, MD, PhD
Memorial Sloan Kettering Cancer Center
Srimoyee Ghosh, PhD
Tesaro
Jeanine Pignatelli, PhD
Pfizer
Sarwish Rafiq, PhD
Memorial Sloan Kettering Cancer Center
Sridhar Ramaswamy, MD
Tesaro
9:00 AM

Welcome Remarks

Speaker

Sridhar Ramaswamy, MD
Tesaro
9:15 AM

Keynote Lecture -Tumor Immunology and Immunotherapy

Speaker

Miriam Merad, MD, PhD
Icahn School of Medicine at Mount Sinai

Session 4: Beyond Cancer Biology: Learning from Immunity

Session Chairperson
Sridhar Ramaswamy, MD, Tesaro
10:00 AM

Functional Profiling of the Gut Microbiota

Speaker

Noah Palm, PhD
Yale School of Medicine
10:30 AM

Networking Coffee Break

11:00 AM

The PD-L1/PD1 Pathways in Autoimmune Diabetes

Speaker

Paolo Fiorina, MD, PhD
Harvard Medical School
11:30 AM

Immunotherapy: What’s Genes Got to do with it?

Speaker

Timothy Chan, MD, PhD
Memorial Sloan Kettering Cancer Center

Session 5: Data Blitz Presentations (selected from poster abstract submissions)

Session Chairperson
Sridhar Ramaswamy, MD, Tesaro
12:00 PM

Lineage–tracing reveals a unique contribution of embryonic macrophages to NSCLC

Speaker

María Casanova-Acebes, PhD (Merad Laboratory)
Icahn School of Medicine at Mount Sinai
12:05 PM

CTNNB1 (Beta-Catenin) Activation Promotes Immune Escape and Resistance to Anti-PD-1 Immunotherapy in Hepatocellular Carcinoma

Speaker

Marina Ruiz De Galaretta, PhD (Lujambio Lab)
Icahn School of Medicine at Mount Sinai
12:10 PM

Networking Lunch

Session 6: Breakout Sessions

1:15 PM - 2:15 PM

Track A: Bispecific Antibody Therapeutics

Jane Gross, PhD
Aptevo Therapeutics

Track B: Vaccine as a foundation for combination immunotherapy

James Hodge, PhD, MBA
National Cancer Institute

Track C: The Microbiome in Immuno-oncology

Jennifer Wargo, MD
MD Anderson Cancer Center

Session 7: Clinical Responses and Tumor Dynamics

Session Chairperson
George Zavoico, PhD, B. Riley FBR
2:15 PM

CAR T-Cell Therapy of Cancer

Speaker

Renier Brentjens, MD, PhD
Memorial Sloan Kettering Cancer Center
2:45 PM

Switching on the Full Potency of Adoptive T-Cell Therapy Using Synthetic Biology Tools

Speaker

David Spencer, PhD
Bellicum Therapeutics
3:15 PM

Networking Coffee Break

3:45 PM

The Role of the Microbiome in Response to Cancer Therapy

Speaker

Jennifer Wargo, MD
MD Anderson Cancer Center
4:15 PM

Probody Therapeutics, Reinventing Therapeutic Antibodies for the Treatment of Cancer

Speaker

Rachel Humphrey, MD
CytomX Therapeutics
4:45 PM

CAR T-Cells in Immunotherapy

Speaker

Marcella V Maus, MD, PhD *
Harvard Medical School ( *not participating in webinar)
5:15 PM

Closing Remarks

Speaker

George Zavoico, PhD
B. Riley FBR
5:30 PM

Conference Adjourns