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Genome Integrity Discussion Group December 2018


for Members

Genome Integrity Discussion Group December 2018

Monday, December 3, 2018, 1:00 PM - 5:25 PM EST

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York

Presented By

Genome Integrity Discussion Group

The New York Academy of Sciences


The greater New York metropolitan area is unparalleled in the concentration of world leading research on chromosome biology and function, as well as for research at the interface between chromosome integrity and the dynamics of malignancy. The Genome Integrity Discussion Group capitalizes on this concentration of excellence, providing a forum for interaction between basic- and clinically-oriented research groups working in these fields. These meetings facilitate synergy between labs, and provide a context in which previously unappreciated complementarities can be revealed.

In that spirit, the talks cover a broad range of areas including the DNA damage response and cancer predisposition, DNA replication, transcription, chromatin modification, recombination, cell cycle control, telomeres, chromosome segregation, epigenetic states, as well as the emergence of new technologies relevant to research in genome integrity. Although a primary focus is upon basic mechanisms and processes, these areas are pertinent to cancer and myriad human disease states.

Call for Student/Postdoc Presentation Abstracts: Deadline November 2, 2018

Please submit abstracts in CSHL format with file name via email to Professor Symington at by November 2, 2018, for consideration.


Nonmember Academia, Faculty, etc.
Nonmember Corporate, Other
Nonmember Not for Profit
Nonmember Student, Undergrad, Grad, Fellow
Member Student, Post-Doc, Fellow
Jean Gautier, PhD,Columbia University Irving School of Medicine
Jean Gautier, PhD,
Columbia University Irving School of Medicine
Scott Keeney, PhD,Memorial Sloan Kettering Cancer Center
Scott Keeney, PhD,
Memorial Sloan Kettering Cancer Center
Lorraine S. Symington, PhD,Columbia University Irving School of Medicine
Lorraine S. Symington, PhD,
Columbia University Irving School of Medicine
Susan L. Smith, PhD,NYU Langone Medical Center
Susan L. Smith, PhD,
NYU Langone Medical Center
Sara Donnelly, PhD,The New York Academy of Sciences
Sara Donnelly, PhD,
The New York Academy of Sciences
Sonya Dougal, PhD,The New York Academy of Sciences
Sonya Dougal, PhD,
The New York Academy of Sciences


Kim McKim, PhD,
Rutgers, The State University of New Jersey
Ben Black, PhD,
Perelman School of Medicine University of Pennsylvania
Titia de Lange, PhD,
The Rockefeller University
Lorraine Symington, PhD,
Columbia University Irving Medical Center

Program Supporters


December 03, 2018

1:00 PM

Registration Opens

1:30 PM

Welcome and Introductory Remarks


Alison Carley, PhD
The New York Academy of Sciences
Lorraine S. Symington, PhD
Columbia University
1:40 PM

How Centromeric Chromatin Organizes the Chromosome/Kinetochore Interface


Ben Black, PhD
University of Pennsylvania
2:10 PM

How ATRX Loss Contributes to ALT


Titia de Lange, PhD
The Rockefeller University
2:40 PM

Signatures of Rearrangements Across 2800 Cancer Genomes


Kevin Hadi (Imielinski Lab)
Weill Cornell Medicine
2:55 PM

Coffee Break

3:25 PM

Translesion Polymerase Kappa-dependent DNA Synthesis Underlies Replication Fork Recovery


Peter Tonzi (Huang Lab)
New York University School of Medicine
3:40 PM

Regulation of Meiotic Spindle Assembly, Sister Chromatid Cohesion and Biorientation in Drosophila Oocytes


Kim McKim, PhD
Rutgers University
4:10 PM

DNA Polymerase Delta Synthesizes Both Strands During Break-Induced Replication


Lorraine Symington, PhD
Columbia University
4:40 PM

Networking Reception

5:25 PM