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Genome Integrity Discussion Group February 2018


for Members

Genome Integrity Discussion Group February 2018

Monday, February 5, 2018, 1:30 PM - 5:30 PM

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York, USA

Presented By

Genome Integrity Discussion Group

The New York Academy of Sciences


The connection between cancer and genome integrity is widely appreciated. Importantly, the greater New York Metropolitan area is unparalleled in the concentration of world leading research on chromosome biology and function, as well as for research at the interface between chromosome integrity and the dynamics of malignancy. The Genome Integrity Discussion Group capitalize on this concentration of excellence, providing a forum for interaction between basic- and clinically-oriented research groups working in these fields. These meetings not only facilitate synergy between labs, but also provide a context in which previously unappreciated complementarities can be revealed.

In that spirit, the talks will cover a broad range of areas, including, but not limited to the DNA damage response and cancer predisposition, DNA replication, transcription, chromatin modification, recombination, cell cycle control, telomeres, chromosome segregation, epigenetic states, as well as the emergence of new technologies relevant to research in genome integrity. Although a primary focus is upon basic mechanisms and processes, these areas are pertinent to cancer and myriad human disease states, and it is expected that this will be reflected in the substance of our discussions. At each of the meetings, two early career scientists (students or postdocs) are selected to present data.

Genome Integrity Discussion Group meetings are organized under the leadership of Scott Keeney (Memorial Sloan Kettering Cancer Center), Susan Smith (NYU Langone Medical Center), and Lorraine Symington (Columbia University Irving Medical Center).

Call for Student/Postdoc Presentation Abstracts: Deadline January 12, 2018

Two abstracts will be selected for short talks by students/postdocs. Please submit abstracts in CSHL format with file name via email to Professor Keeney at by January 12, 2018, for consideration.


Nonmember Academia, Faculty, etc.
Nonmember Corporate, Other
Nonmember Not for Profit
Nonmember Student, Undergrad, Grad, Fellow
Member Student, Post-Doc, Fellow


Scott Keeney, PhD, Memorial Sloan Kettering Cancer Center
Scott Keeney, PhD, Memorial Sloan Kettering Cancer Center
Susan Smith, PhD, NYU Langone Medical Center
Susan Smith, PhD, NYU Langone Medical Center
Lorraine Symington, PhD, Columbia University Irving Medical Center
Lorraine Symington, PhD, Columbia University Irving Medical Center
Sonya Dougal, PhD, The New York Academy of Sciences
Sonya Dougal, PhD, The New York Academy of Sciences


February 05, 2018

1:00 PM

Registration Opens

1:30 PM

Welcome and Introductory Remarks


Sonya Dougal, PhD
The New York Academy of Science
Scott Keeney, PhD
Memorial Sloan Kettering Cancer Center
1:40 PM

Searching for Telomerase Regulators


Virginia Zakian, PhD
Princeton University
2:10 PM

Dynamic Interactions of Virus and Host Genomes During Infection


Matthew Weitzman, PhD
University of Pennsylvania
2:40 PM

Ends: A Means to Establishing Chromosome Size-Bias


Viji Subramanian, PhD
New York University (Hochwagen Lab)
2:55 PM

Coffee Break

3:25 PM

CIN as a Driver of Metastasis


Samuel Bakhoum, MD, PhD
Weill Cornell Medicine (Cantley Lab)
3:40 PM

Aneuploidy and Chromosomal Instability in Tumorigenesis


Jason Sheltzer, PhD
Cold Spring Harbor Laboratory
4:10 PM

The Role of Polymerase Theta in Cancer


Agnel Sfeir, PhD
New York University School of Medicine
4:40 PM

Networking Reception

5:30 PM