Neuro-Immunology: The Impact of Immune Function on Alzheimer’s Disease
Tuesday, September 25, 2018
The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York
The New York Academy of Sciences
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder for which there are currently no effective treatments. High profile setbacks in clinical trials of compounds targeting amyloid-beta and tau emphasize the need to look beyond these canonical contributions to AD, in order to better understand the pathological processes that underlie neurodegeneration and thus to ultimately design more effective approaches for curing the disease. Growing evidence supports a role for inflammation as a major causative and/or exacerbating factor in AD onset and progression, providing important insight into pathobiology and a wellspring of novel putative treatment targets. This one-day symposium will build upon genetic evidence for inflammation in AD, highlighting cutting-edge science that explores the mechanisms that underlie this intersection between neurology and immunology, and parse the contributions of the immune system to the range of behaviors evidenced over the clinical course of AD.
Scientific Organizing Committee