
Available via
WEBINAR
Extracellular Vesicles in Diagnostics and Therapeutics
Tuesday, February 19, 2019, 8:30 AM - 5:30 PM EST
The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York
The field of extracellular vesicles (EV) research has expanded dramatically in recent years, providing new insights into their critical biological functions as well as their therapeutic and diagnostic applications. A heterogeneous pool of lipid-enclosed vesicles, EVs are associated with a wide variety of cell types and encapsulate molecular cargoes such as miRNAs, mRNAs, proteins and lipids. Once thought of simply as carriers of metabolic waste, we now know that these vesicles perform a wide range of tissue-specific functions and are important for cell-cell communication.
The relative simplicity of EV isolation techniques from non-invasive biofluid sampling, in addition to the wealth of information contained therein, makes EV a promising tool for diagnostics and biomarker discovery. Furthermore, EVs are gaining traction as therapeutics themselves, as a unique drug delivery system for a potentially wide variety of indications.
In this symposium, we will review the most recent advances in EV research and their increasing impact on diagnostics and drug development for cancer, neurodegenerative disease, metabolic disease, and cardiovascular disease.
Registration
Member
By 01/08/2019
$90
After 01/08/2019
$130
Nonmember Academia, Faculty, etc.
By 01/08/2019
$180
After 01/08/2019
$260
Nonmember Corporate, Other
By 01/08/2019
$250
After 01/08/2019
$350
Nonmember Not for Profit
By 01/08/2019
$180
After 01/08/2019
$260
Nonmember Student, Undergrad, Grad, Fellow
By 01/08/2019
$100
After 01/08/2019
$145
Member Student, Post-Doc, Fellow
By 01/08/2019
$50
After 01/08/2019
$70
Member
$30
Nonmember Academia, Faculty, etc.
$65
Nonmember Corporate, Other
$85
Nonmember Not for Profit
$65
Nonmember Student, Undergrad, Grad, Fellow
$45
Member Student, Post-Doc, Fellow
$15
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Tuesday
February 19, 2019
8:30 AM
Continental Breakfast and Registration
9:00 AM
Introduction and Welcome Remarks
Speakers
Alison Carley, PhD
The New York Academy of Sciences
Alissa Weaver, PhD
Vanderbilt University School of Medicine
9:15 AM
Keynote Address ~ Extracellular Vesicles: Biology and Translational Potential
Speaker
Xandra Breakefield, PhD
Harvard University
Session 1: Exosome Biology and Role in Pathway Regulation
Session Chairperson
Richard A. Cerione, PhD, Cornell University
10:00 AM
Probing the Mechanisms of Extracellular Vesicle Biogenesis and Function in Cancer and Development
Speaker
Richard A. Cerione, PhD
Cornell University
10:30 AM
Networking Coffee Break
11:00 AM
Role of Exosomes in Cancer Cell Migration and Metastasis
Speaker
Alissa Weaver, PhD
Vanderbilt University School of Medicine
11:30 AM
Extracellular Vesicles in Fatty Liver Disease
Speaker
Harmeet Malhi, MBBS
Mayo Clinic
Session 2: Data Blitz Presentations
Session Chairperson
Jemy A. Gutierrez, PhD, Pfizer
12:00 PM
Diagnosis of Traumatic Brain Injury Using miRNA Signatures in Nanomagnetically Isolated Brain-derived Extracellular Vesicles
Speaker
Jina Ko, PhD
Massachusetts General Hospital
12:05 PM
Non-Genetic Based Approaches Toward Engineering Cargo Into and Onto Extracellular Vesicles
Speaker
Saigopalakrishna Yerneni, MS
Carnegie Mellon University
12:10 PM
A Lipase-independent Pathway of Lipid Release and Immune Modulation by Adipocytes via Exosomes
Speaker
Stephen E. Flaherty III
Columbia University
12:15 PM
Networking Lunch and Poster Session
Session 3: Exosomes as Biomarkers and Therapeutics
Session Chairperson
Theresa Wilson, PhD, Pfizer
1:15 PM
Exosomes in Diagnostics and Therapeutics of Cardiovascular Medicine
Speaker
Susmita Sahoo, PhD
Icahn School of Medicine at Mount Sinai
1:45 PM
Tumor-derived Exosomes and Exomeres Promote Organotropic Metastasis and Systemic Disease
Speaker
David C. Lyden, MD, PhD
Weill Cornell Medical College
2:15 PM
Current State of Exosome Based Biomarkers
Speaker
Johan Skog, PhD
Exosome Diagnostics Inc
2:45 PM
Networking Coffee Break
3:15 PM
Extracellular Vesicles as Drug Delivery System to the Central Nervous System
Speaker
Elena V. Batrakova, PhD
Eshelman School of Pharmacy, University of North Carolina at Chapel Hill
3:45 PM
Panel Discussion: Current Gaps and Challenges in the Utility of Extracellular Vesicles for Biomarkers and Therapeutics
Speakers
Moderator: Xandra Breakefield, PhD
Harvard University
Elena V. Batrakova, PhD
Eshelman School of Pharmacy, University of North Carolina at Chapel Hill
Johan Skog, PhD
Exosome Diagnostics Inc.
4:15 PM
Poster Session & Networking Reception
5:15 PM
F1000 Poster Prize Presentation and Closing Remarks
5:30 PM