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Extracellular Vesicles in Diagnostics and Therapeutics

Available via

WEBINAR

Extracellular Vesicles in Diagnostics and Therapeutics

Tuesday, February 19, 2019, 8:30 AM - 5:30 PM

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York

Presented By

The Biochemical Pharmacology Discussion Group

The New York Academy of Sciences

 

The field of extracellular vesicles (EV) research has expanded dramatically in recent years, providing new insights into their critical biological functions as well as their therapeutic and diagnostic applications. A heterogeneous pool of lipid-enclosed vesicles, EVs are associated with a wide variety of cell types and encapsulate molecular cargoes such as miRNAs, mRNAs, proteins and lipids. Once thought of simply as carriers of metabolic waste, we now know that these vesicles perform a wide range of tissue-specific functions and are important for cell-cell communication.

The relative simplicity of EV isolation techniques from non-invasive biofluid sampling, in addition to the wealth of information contained therein, makes EV a promising tool for diagnostics and biomarker discovery. Furthermore, EVs are gaining traction as therapeutics themselves, as a unique drug delivery system for a potentially wide variety of indications.

In this symposium, we will review the most recent advances in EV research and their increasing impact on diagnostics and drug development for cancer, neurodegenerative disease, metabolic disease, and cardiovascular disease.

Registration

Member
By 01/08/2019
$90
After 01/08/2019
$130
Nonmember Academia, Faculty, etc.
By 01/08/2019
$180
After 01/08/2019
$260
Nonmember Corporate, Other
By 01/08/2019
$250
After 01/08/2019
$350
Nonmember Not for Profit
By 01/08/2019
$180
After 01/08/2019
$260
Nonmember Student, Undergrad, Grad, Fellow
By 01/08/2019
$100
After 01/08/2019
$145
Member Student, Post-Doc, Fellow
By 01/08/2019
$50
After 01/08/2019
$70
Member
$30
Nonmember Academia, Faculty, etc.
$65
Nonmember Corporate, Other
$85
Nonmember Not for Profit
$65
Nonmember Student, Undergrad, Grad, Fellow
$45
Member Student, Post-Doc, Fellow
$15
Earlybird Registration:
0
days
left
Deadline:
0
days
left

Keynote Speaker

Xandra Breakefield
Xandra Breakefield, PhD,
Harvard University

Speakers

Elena V. Batrakova, PhD
Elena V. Batrakova, PhD

Eshelman School of Pharmacy, University of North Carolina at Chapel Hill

Richard Cerione
Richard A. Cerione, PhD

Cornell University

David C. Lyden, MD, PhD
David C. Lyden, MD, PhD

Weill Cornell Medical College

Harmeet Malhi
Harmeet Malhi, MBBS

Mayo Clinic

Susmita Sahoo
Susmita Sahoo, PhD

Icahn School of Medicine at Mount Sinai

Johan Skog
Johan Skog, PhD

Exosome Diagnostics Inc

Alissa Weaver
Alissa Weaver, PhD

Vanderbilt University School of Medicine

Jina Ko, PhD
Jina Ko, PhD

Massachusetts General Hospital

Stephen E. Flaherty III
Stephen E. Flaherty III

Columbia University

Saigopalakrishna Yerneni, MS
Saigopalakrishna Yerneni, MS

Carnegie Mellon University

Scientific Organizing Committee

Richard A. Cerione, PhD,
Cornell University
Jemy A. Gutierrez, PhD,
Pfizer
Jorge Schettini, PhD,
Pfizer
Claire Steppan, PhD,
Pfizer
Gregory Tesz, PhD,
Pfizer
Theresa Wilson, PhD,
Pfizer
Alissa Weaver, PhD,
Vanderbilt University School of Medicine
Sonya Dougal, PhD,
The New York Academy of Sciences
Alison Carley, PhD,
The New York Academy of Sciences





Tuesday

February 19, 2019

8:30 AM

Continental Breakfast and Registration

9:00 AM

Introduction and Welcome Remarks

Speakers

Alison Carley, PhD
The New York Academy of Sciences
Alissa Weaver, PhD
Vanderbilt University School of Medicine
9:15 AM

Keynote Address ~ Extracellular Vesicles: Biology and Translational Potential

Speaker

Xandra Breakefield, PhD
Harvard University

Session 1: Exosome Biology and Role in Pathway Regulation

Session Chairperson
Richard A. Cerione, PhD, Cornell University
10:00 AM

Probing the Mechanisms of Extracellular Vesicle Biogenesis and Function in Cancer and Development

Speaker

Richard A. Cerione, PhD
Cornell University
10:30 AM

Networking Coffee Break

11:00 AM

Role of Exosomes in Cancer Cell Migration and Metastasis

Speaker

Alissa Weaver, PhD
Vanderbilt University School of Medicine
11:30 AM

Extracellular Vesicles in Fatty Liver Disease

Speaker

Harmeet Malhi, MBBS
Mayo Clinic

Session 2: Data Blitz Presentations

Session Chairperson
Jemy A. Gutierrez, PhD, Pfizer
12:00 PM

Diagnosis of Traumatic Brain Injury Using miRNA Signatures in Nanomagnetically Isolated Brain-derived Extracellular Vesicles

Speaker

Jina Ko, PhD
Massachusetts General Hospital
12:05 PM

Non-Genetic Based Approaches Toward Engineering Cargo Into and Onto Extracellular Vesicles

Speaker

Saigopalakrishna Yerneni, MS
Carnegie Mellon University
12:10 PM

A Lipase-independent Pathway of Lipid Release and Immune Modulation by Adipocytes via Exosomes

Speaker

Stephen E. Flaherty III
Columbia University
12:15 PM

Networking Lunch and Poster Session

Session 3: Exosomes as Biomarkers and Therapeutics

Session Chairperson
Theresa Wilson, PhD, Pfizer
1:15 PM

Exosomes in Diagnostics and Therapeutics of Cardiovascular Medicine

Speaker

Susmita Sahoo, PhD
Icahn School of Medicine at Mount Sinai
1:45 PM

Tumor-derived Exosomes and Exomeres Promote Organotropic Metastasis and Systemic Disease

Speaker

David C. Lyden, MD, PhD
Weill Cornell Medical College
2:15 PM

Current State of Exosome Based Biomarkers

Speaker

Johan Skog, PhD
Exosome Diagnostics Inc
2:45 PM

Networking Coffee Break

3:15 PM

Extracellular Vesicles as Drug Delivery System to the Central Nervous System

Speaker

Elena V. Batrakova, PhD
Eshelman School of Pharmacy, University of North Carolina at Chapel Hill
3:45 PM

Panel Discussion: Current Gaps and Challenges in the Utility of Extracellular Vesicles for Biomarkers and Therapeutics

Speakers

Moderator: Xandra Breakefield, PhD
Harvard University
Elena V. Batrakova, PhD
Eshelman School of Pharmacy, University of North Carolina at Chapel Hill
Johan Skog, PhD
Exosome Diagnostics Inc.
4:15 PM

Poster Session & Networking Reception

5:15 PM

F1000 Poster Prize Presentation and Closing Remarks

5:30 PM

Adjourn

To view full attendee list, you must first register for the event, then log in to the Academy website. This list is provided for the personal, noncommercial and informational use only of event attendees, in a manner that is consistent with the New York Academy of Sciences’ mission, goals and activities.
  • AbbVie

  • Alzheimer's Drug Discovery Foundation

  • ARCONS Institute for Applied Research & Didactics

  • Boehringer Ingelheim Pharmaceuticals

  • Carnegie Mellon University

  • Cellex Life Science

  • Century Innovations

  • Cold Spring Harbor Laboratory

  • Columbia University

  • Columbia University Irving Medical Center

  • Columbia University School of Public Health

  • Cornell University

  • Exosome Diagnostics

  • FiberCell Systems Inc.

  • Georgetown University

  • Harvard Medical School, Mass General

  • Harvard School of Public Health

  • Henry Ford Hospital

  • Hunter College, CUNY

  • Icahn School of Medicine at Mount Sinai

  • INmune Bio

  • Johns Hopkins University School of Medicine

  • Lucerna, Inc.

  • Massachusetts General Hospital

  • Mayo Clinic

  • Monmouth University

  • Nathan Kline Institute for Psychiatric Research

  • National Institute of Health Sciences

  • Nature Biotechnology

  • Particle Metrix

  • Pfizer

  • Pfizer Centers for Therapeutic Innovation

  • Pfizer Global Research and Development

  • Pfizer Inc

  • Pleasantville Friends of STEM,Inc.

  • Regeneron Pharmaceuticals, Inc

  • Renal Research Institute

  • Rutgers Graduate School of Biomedical Sciences

  • Rutgers University Robert Wood Johnson Medical School

  • Seton Hall University

  • Southern Connecticut State University

  • SQI Diagnostics

  • St. Johns University

  • St. John's University

  • St. Johns University, NY

  • SWAP writer

  • The Columbia University School of Medicine

  • The Icahn School of Medicine at Mount Sinai

  • The Telmarc Group

  • The University of Pennsylvania

  • Touro College

  • University of North Carolina at Chapel Hill

  • University of Pennsylvania School of Medicine

  • Vanderbilt University School of Medicine

  • Viola Advisory LLC

  • Weill Cornell Graduate School of Medical Sciences

  • Weill Cornell Medical College

  • Weill Cornell Medicine