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Genome Integrity Discussion Group April 2019

Genome Integrity Discussion Group April 2019

Monday, April 1, 2019, 1:00 PM - 5:25 PM EDT

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York

Presented By

Genome Integrity Discussion Group

The New York Academy of Sciences

 

The greater New York metropolitan area is unparalleled in the concentration of world leading research on chromosome biology and function, as well as for research at the interface between chromosome integrity and the dynamics of malignancy. The Genome Integrity Discussion Group capitalizes on this concentration of excellence, providing a forum for interaction between basic- and clinically-oriented research groups working in these fields. These meetings facilitate synergy between labs, and provide a context in which previously unappreciated complementarities can be revealed.

In that spirit, the talks cover a broad range of areas including the DNA damage response and cancer predisposition, DNA replication, transcription, chromatin modification, recombination, cell cycle control, telomeres, chromosome segregation, epigenetic states, as well as the emergence of new technologies relevant to research in genome integrity. Although a primary focus is upon basic mechanisms and processes, these areas are pertinent to cancer and myriad human disease states.

Call for Student/Postdoc Presentation Abstracts: Deadline March 1, 2019

Please submit abstracts in CSHL format with file name NYAS.name.doc via email to Professor Symington at lss5@cumc.columbia.edu by March 1, 2019, for consideration.

Registration

Member
$10
Nonmember Academia, Faculty, etc.
$80
Nonmember Corporate, Other
$95
Nonmember Not for Profit
$80
Nonmember Student, Undergrad, Grad, Fellow
$40
Member Student, Post-Doc, Fellow
$5

Organizers

Jean Gautier, PhD,Columbia University Irving School of Medicine
Jean Gautier, PhD,
Columbia University Irving School of Medicine
Scott Keeney, PhD,Memorial Sloan Kettering Cancer Center
Scott Keeney, PhD,
Memorial Sloan Kettering Cancer Center
Susan L. Smith, PhD,NYU Langone Medical Center
Susan L. Smith, PhD,
NYU Langone Medical Center
Lorraine S. Symington, PhD,Columbia University Irving School of Medicine
Lorraine S. Symington, PhD,
Columbia University Irving School of Medicine
Alison Carley, PhD,The New York Academy of Sciences
Alison Carley, PhD,
The New York Academy of Sciences

Speakers

Samuel Bunting, PhD,
Rutgers, The State University of New Jersey
Maria Jasin, PhD,
Memorial Sloan Kettering Cancer Center
Prasad Jallepalli, MD, PhD,
Memorial Sloan Kettering Cancer Center
Jane Skok, PhD,
New York University Langone Medical Center

Monday

April 01, 2019

1:00 PM

Registration Opens

1:30 PM

Welcome and Introductory Remarks

Speakers

Alison Carley, PhD
The New York Academy of Sciences
Jean Gautier, PhD
Columbia University Irving Medical Center
1:40 PM

53BP1 Protects Cells Against Oncogenic Replication Stress

Speaker

Samuel F. Bunting, PhD
Rutgers University
2:10 PM

Intricacies of Homologous Recombination: Roles of a Non-Canonical Rad51 Paralog Complex

Speaker

Maria Jasin, PhD
Memorial Sloan Kettering Cancer Center
2:40 PM

PARP Inhibitors Trap PARP1 at the DNA Damage Foci Without Affecting PARP1 Exchange In Vivo

Speaker

Zhengping Shao, MD, PhD
Columbia University (Zha lab)
2:55 PM

Coffee Break

3:25 PM

SIRT7 is Required for Chromosome Synapsis and Deacetylation of Histone H3K18 during Prophase I of Female Meiosis

Speaker

Berta Vazquez Prat
Rutgers University (Schindler lab)
3:40 PM

Human DDK Ensures Complete DNA Replication by Sustaining Fork Elongation and Counteracting Origin Inhibition by the S Phase Checkpoint

Speaker

Prasad Jallepalli, MD, PhD
Memorial Sloan Kettering Cancer Center
4:10 PM

CTCFL and its Impact on Gene Regulation and Interplay with CTCF Function

Speaker

Jane Skok, PhD
New York University School of Medicine
4:40 PM

Networking Reception