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Targeting Immunometabolism in Autoimmune Diseases and Inflammation

Available via

WEBINAR

Targeting Immunometabolism in Autoimmune Diseases and Inflammation

Tuesday, October 22, 2019, 8:30 AM - 5:30 PM

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York

Presented By

The Biochemical Pharmacology Discussion Group

The New York Academy of Sciences

 

A large unmet medical need persists across the spectrum of autoimmune and inflammatory diseases. Emerging evidence suggests that immune cell fate is tightly regulated by changes in metabolic programming, including aerobic glycolysis (the Warburg effect), fatty acid synthesis and oxidation, and mitochondrial activity. Modulation of these pathways by cytokines, growth factors, and microbial products, as well as nutrient availability, controls the ability of lymphocytes to proliferate and produce specific immune effector molecules. Consequently, changes in immune cell metabolism can have a major impact on the progression and resolution of autoimmune and inflammatory diseases.

This symposium will explore the immunometabolic pathways that govern innate and adaptive immune cell activation, with a view to highlighting core pathways and specific enzymes that are likely therapeutic targets for autoimmune diseases and dysregulated inflammation.

Registration

Member
By 09/10/2019
$90
After 09/10/2019
$130
Nonmember Academia, Faculty, etc.
By 09/10/2019
$180
After 09/10/2019
$260
Nonmember Corporate, Other
By 09/10/2019
$250
After 09/10/2019
$350
Nonmember Not for Profit
By 09/10/2019
$180
After 09/10/2019
$260
Nonmember Student, Undergrad, Grad, Fellow
By 09/10/2019
$100
After 09/10/2019
$145
Member Student, Post-Doc, Fellow
By 09/10/2019
$50
After 09/10/2019
$70
Member
$30
Nonmember Academia, Faculty, etc.
$65
Nonmember Corporate, Other
$85
Nonmember Not for Profit
$65
Nonmember Student, Undergrad, Grad, Fellow
$45
Member Student, Post-Doc, Fellow
$15
Earlybird Registration:
0
days
left
Deadline:
0
days
left

Scientific Organizing Committee

J. Perry Hall, PhD
J. Perry Hall, PhD

Pfizer

Gokhan Hotamisligil, MD, PhD
Gokhan Hotamisligil, MD, PhD

Harvard University

Luke O'Neill, PhD
Luke O'Neill, PhD

Trinity College Dublin

Jeffrey Rathmell, PhD
Jeffrey Rathmell, PhD

Vanderbilt University

Claire Steppan, PhD
Claire Steppan, PhD

Pfizer

Tom Wynn, PhD
Tom Wynn, PhD

Pfizer

Sara Donnelly, PhD
Sara Donnelly, PhD

The New York Academy of Sciences

Keynote Speakers

Susan Kaech, PhD
Susan Kaech, PhD

The Salk Institute

Jeffrey Rathmell, PhD
Jeffrey Rathmell, PhD

Vanderbilt University

Speakers

Anthony Ferrante, MD, PhD
Anthony Ferrante, MD, PhD

Columbia University

Alyssa Hasty, PhD
Alyssa Hasty, PhD

Vanderbilt University

Claudia Kemper, PhD
Claudia Kemper, PhD

National Institutes of Health

Russell Jones, PhD
Russell Jones, PhD

Van Andel Research Institute

Laurence Morel, PhD
Laurence Morel, PhD

University of Florida

Jonathan Powell, MD, PhD
Jonathan Powell, MD, PhD

Johns Hopkins University School of Medicine

Chaoran Li, PhD
Chaoran Li, PhD

Harvard Medical School





Tuesday

October 22, 2019

8:30 AM

Breakfast and Registration

9:00 AM

Introduction and Welcome Remarks

Speakers

Sara Donnelly, PhD
The New York Academy of Sciences
J. Perry Hall, PhD
Pfizer
9:15 AM

Kenote Address: Stimulating Immunological Memory

Speaker

Susan Kaech, PhD
The Salk Institute

Session 1: Cellular and Systemic Metabolic Mechanisms in Immunity

Session Chairperson
J. Perry Hall, PhD, Pfizer
10:00 AM

Life History and Regulation of Adipose Tissue Tregs

Speaker

Chaoran Li, PhD
Harvard Medical School
10:30 AM

Networking Coffee Break

11:00 AM

Unexpected Roles for the Complosome in Normal Cell Physiology

Speaker

Claudia Kemper, PhD
National Heart, Lung, and Blood Institute, National Institutes of Health
11:30 AM

Modulation of the Immune System by Adipocytes

Speaker

Anthony Ferrante, MD, PhD
Columbia University

Session 2: Data Blitz Talks

Session Chairperson
Jeffrey Rathmell, PhD, Vanderbilt University
12:00 PM

Single-Cell Metabolic States Organize the Functional Landscape of Human T-Cells

Speaker

Felix Hartmann, PhD
Stanford University
12:05 PM

The Immune Checkpoint B7-H3 (CD276) Protects against Obesity

Speaker

Elodie Picarda, PhD
Albert Einstein College of Medicine
12:10 PM

Identification of Commensal Gut Bacteria with Potential to Influence Autoimmunity

Speaker

Varsha Raghavan, PhD**
NYU School of Medicine (**Not Participating in Webinar)
12:15 PM

Networking Lunch and Poster Session

Speakers

Odd number posters: 12:45pm - 1:15pm
Even number posters: 1:15pm - 1:45pm

Session 3: Targeting Immunometabolism in Disease

Session Chairperson
Tom Wynn, PhD, Pfizer
1:45 PM

Regulating T Cell Responses by Targeting One Carbon Metabolism

Speaker

Russell Jones, PhD
Van Andel Research Institute
2:15 PM

Targeting Immunometabolism: Cellular Selectivity Based on Demand

Speaker

Jonathan Powell, MD, PhD
Johns Hopkins University School of Medicine
2:45 PM

Contribution of Iron to Intrinsic and Extrinsic Macrophage Immunometabolism

Speaker

Alyssa Hasty, PhD
Vanderbilt University
3:15 PM

Networking Coffee Break

3:45 PM

Targeting Immunometabolism in Lupus

Speaker

Laurence Morel, PhD
University of Florida
4:15 PM

Keynote Address: Fueling T Cells for Inflammation and Immunity

Speaker

Jeffrey Rathmell, PhD
Vanderbilt University
5:00 PM

Closing Remarks

Speaker

Tom Wynn, PhD
Pfizer
5:15 PM

Networking Reception

6:15 PM

Adjourn