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Targeting Immunometabolism in Autoimmune Diseases and Inflammation

Available via

WEBINAR

Targeting Immunometabolism in Autoimmune Diseases and Inflammation

Tuesday, October 22, 2019, 8:30 AM - 5:30 PM

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York

Presented By

The Biochemical Pharmacology Discussion Group

The New York Academy of Sciences

 

A large unmet medical need persists across the spectrum of autoimmune and inflammatory diseases. Emerging evidence suggests that immune cell fate is tightly regulated by changes in metabolic programming, including aerobic glycolysis (the Warburg effect), fatty acid synthesis and oxidation, and mitochondrial activity. Modulation of these pathways by cytokines, growth factors, and microbial products, as well as nutrient availability, controls the ability of lymphocytes to proliferate and produce specific immune effector molecules. Consequently, changes in immune cell metabolism can have a major impact on the progression and resolution of autoimmune and inflammatory diseases.

This symposium will explore the immunometabolic pathways that govern innate and adaptive immune cell activation, with a view to highlighting core pathways and specific enzymes that are likely therapeutic targets for autoimmune diseases and dysregulated inflammation.

Call for Abstracts

Abstract submissions are invited for a poster session and short talks. For complete submission instructions, please visit our online portal. The deadline for abstract submission is  August 23, 2019.

Registration

Member
By 09/10/2019
$90
After 09/10/2019
$130
Nonmember Academia, Faculty, etc.
By 09/10/2019
$180
After 09/10/2019
$260
Nonmember Corporate, Other
By 09/10/2019
$250
After 09/10/2019
$350
Nonmember Not for Profit
By 09/10/2019
$180
After 09/10/2019
$260
Nonmember Student, Undergrad, Grad, Fellow
By 09/10/2019
$100
After 09/10/2019
$145
Member Student, Post-Doc, Fellow
By 09/10/2019
$50
After 09/10/2019
$70
Member
$30
Nonmember Academia, Faculty, etc.
$65
Nonmember Corporate, Other
$85
Nonmember Not for Profit
$65
Nonmember Student, Undergrad, Grad, Fellow
$45
Member Student, Post-Doc, Fellow
$15
Earlybird Registration:
22
days
left
Deadline:
5
days
left

Scientific Organizing Committee

J. Perry Hall, PhD
J. Perry Hall, PhD

Pfizer

Gokhan Hotamisligil, MD, PhD
Gokhan Hotamisligil, MD, PhD

Harvard University

Luke O'Neill, PhD
Luke O'Neill, PhD

Trinity College Dublin

Jeffrey Rathmell, PhD
Jeffrey Rathmell, PhD

Vanderbilt University

Claire Steppan, PhD
Claire Steppan, PhD

Pfizer

Tom Wynn, PhD
Tom Wynn, PhD

Pfizer

Sara Donnelly, PhD
Sara Donnelly, PhD

The New York Academy of Sciences

Keynote Speakers

Susan Kaech, PhD
Susan Kaech, PhD

The Salk Institute

Jeffrey Rathmell, PhD
Jeffrey Rathmell, PhD

Vanderbilt University

Speakers

Lydia Lynch, PhD
Lydia Lynch, PhD

Harvard Medical School

Heather Christofk, PhD
Heather Christofk, PhD

University of California Los Angeles

Claudia Kemper, PhD
Claudia Kemper, PhD

National Institutes of Health

Russell Jones, PhD
Russell Jones, PhD

Van Andel Research Institute

Laurence Morel, PhD
Laurence Morel, PhD

University of Florida

Jonathan Powell, MD, PhD
Jonathan Powell, MD, PhD

Johns Hopkins University School of Medicine

Chaoran Li, PhD
Chaoran Li, PhD

Harvard Medical School





Tuesday

October 22, 2019

8:30 AM

Breakfast and Registration

9:00 AM

Introduction and Welcome Remarks

Speakers

Sara Donnelly, PhD
The New York Academy of Sciences
J. Perry Hall, PhD
Pfizer
9:15 AM

Kenote Address (title to be confirmed)

Speaker

Susan Kaech, PhD
The Salk Institute

Session 1: Cellular and Systemic Metabolic Mechanisms in Immunity

Session Chairperson
J. Perry Hall, PhD, Pfizer
10:00 AM

Life History and Regulation of Adipose Tissue Tregs

Speaker

Chaoran Li, PhD
Harvard Medical School
10:30 AM

Networking Coffee Break

11:00 AM

Unexpected Roles for the Complosome in Normal Cell Physiology

Speaker

Claudia Kemper, PhD
National Heart, Lung, and Blood Institute, National Institutes of Health
11:30 AM

The Effects of Obesity and Diet on Immune Cell Functions

Speaker

Lydia Lynch, PhD
Harvard Medical School

Session 2: Data Blitz Talks

Session Chairperson
Jeffrey Rathmell, PhD, Vanderbilt University
12:00 PM

3 Short Talks Selected from Submitted Abstracts

12:15 PM

Networking Lunch and Poster Session

Speakers

Odd number posters: 12:45pm - 1:15pm
Even number posters: 1:15pm - 1:45pm

Session 3: Targeting Immunometabolism in Disease

Session Chairperson
Tom Wynn, PhD, Pfizer
1:45 PM

Metabolic Regulation of T Cell Function

Speaker

Russell Jones, PhD
Van Andel Research Institute
2:15 PM

Targeting Immunometabolism: Cellular Selectivity Based on Demand

Speaker

Jonathan Powell, MD, PhD
Johns Hopkins University School of Medicine
2:45 PM

Control of Immunometabolism in Cancer

Speaker

Heather Christofk, PhD
University of California, Los Angeles
3:15 PM

Networking Coffee Break

3:45 PM

Targeting Immunometabolism in Lupus

Speaker

Laurence Morel, PhD
University of Florida
4:15 PM

Keynote Address: Fueling T Cells for Inflammation and Immunity

Speaker

Jeffrey Rathmell, PhD
Vanderbilt University
5:00 PM

Closing Remarks and Poster Prize Presentation

Speaker

Tom Wynn, PhD
Pfizer
5:15 PM

Networking Reception

6:15 PM

Adjourn