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2020 Ross Prize in Molecular Medicine

WEBINAR

Only

2020 Ross Prize in Molecular Medicine — Mechanisms of RNA Splicing

Friday, October 30, 2020, 1:00 PM - 4:50 PM EDT

Webinar

Presented By

 

The Ross Prize in Molecular Medicine was established in conjunction with the Feinstein Institutes for Medical Research and Molecular Medicine to recognize biomedical scientists whose discoveries have transformed the way medicine is practiced. The awardees are midcareer researchers who have made a significant impact in the understanding of human disease pathogenesis and/or treatment. Moreover, it is anticipated that they will continue to make profound advances in the general field of molecular medicine.

The 2020 Ross Prize in Molecular Medicine will be awarded to Dr. Adrian R. Krainer for his pioneering work in introducing anti-sense therapy in clinical use, and for its successful application to spinal muscular atrophy (SMA).

In addition to studying the mechanisms of RNA splicing, Dr. Krainer uses multidisciplinary approaches to examine the ways in which they go awry in disease, and the means by which faulty splicing can be corrected.  He co-developed the first FDA-approved therapy for the genetic disorder SMA — an illness that has been the leading genetic cause of infant death — based on the biological process of RNA splicing.  This life-saving drug is also the first approved splicing-corrective therapy.

Registration

Individual
$10

Awardee

Adrian R. Krainer, PhD
Adrian R. Krainer, PhD

Cold Spring Harbor Laboratory

Speakers

Michelle L. Hastings
Michelle L. Hastings, PhD

Rosalind Franklin University of Medicine and Science

Edward M. Kaye
Edward M. Kaye, MD

Stoke Therapeutics

Timothy Yu
Timothy Yu, MD, PhD

Boston Children’s Hospital, Harvard Medical School

Friday

October 30, 2020

1:00 PM

Welcome and Introductory Remarks

Speakers

Melanie Brickman Borchard, PhD, MSc
The New York Academy of Sciences
Kevin J. Tracey, MD
The Feinstein Institutes for Medical Research
Jack and Robin Ross
The Feinstein Institutes for Medical Research Board of Directors

Session I: 2020 Ross Prize in Molecular Medicine Presentation and Lecture

1:30 PM

2020 Ross Prize in Molecular Medicine Announcement and Presentation

Speaker

Lars Klareskog, MD, PhD
Karolinska Institute
1:40 PM

2020 Ross Prize in Molecular Medicine Acceptance

Speaker

Adrian R. Krainer, PhD
Cold Spring Harbor Laboratory
1:45 PM

From Base Pairs to Bedside: Antisense Modulation of RNA Splicing

Speaker

Adrian R. Krainer, PhD
Cold Spring Harbor Laboratory
2:45 PM

Break

Session II: Genetics of Neurological Disorders

3:15 PM

RNA-Based Precision Medicine Approach for the Treatment of a Genetic Epilepsy

Speaker

Edward M. Kaye, MD
Stoke Therapeutics
3:45 PM

Splice-switching Antisense Oligonucleotides for the Treatment of Neurological Disorders

Speaker

Michelle L. Hastings, PhD
Rosalind Franklin University of Medicine and Science
4:15 PM

Patient-customized Antisense Oligonucleotides: Early Forays into Individualized Genomic Medicine

Speaker

Timothy Yu, MD, PhD
Boston Children’s Hospital, Harvard Medical School
4:45 PM

Closing Remarks

Speakers

Lars Klareskog, MD, PhD
Karolinska Institute
Melanie Brickman Borchard, PhD, MSc
The New York Academy of Sciences
4:50 PM

Adjourn