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Immune-Stromal Cell Interactions in Wound Healing, Fibrosis and Cancer

WEBINAR

Only

Immune-Stromal Cell Interactions in Wound Healing, Fibrosis and Cancer

Tuesday, June 9, 2020, 11:00 AM - 5:00 PM EDT

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York

Presented By

Biochemical Pharmacology Discussion Group

The New York Academy of Sciences

 

The stromal microenvironment plays critical roles in tissue homeostasis, wound healing and the inflammatory response. Comprised of fibroblasts, the extracellular matrix, endothelial cells, pericytes, and adipocytes — many elements of the stroma have recently been implicated as important modulators of the shape and intensity of local immune responses. Thus, greater knowledge of the interactions between immune cells and stromal components is critical to understand their roles in both normal and pathological scenarios.

This one-day symposium will highlight common mechanisms of reciprocal regulation between stromal constituents and immune cells with the goal of identifying new therapeutic strategies for a variety of diseases including cancer, fibrosis and chronic inflammatory and autoimmune conditions.

Registration

Member
$30
Nonmember Academia, Faculty, etc.
$65
Nonmember Corporate, Other
$85
Nonmember Not for Profit
$65
Nonmember Student, Undergrad, Grad, Fellow
$45
Member Student, Post-Doc, Fellow
$15
Deadline:
0
days
left

Keynote Speakers

Ellen Puré, PhD
Ellen Puré, PhD

University of Pennsylvania

Speakers

Laura Donlin, PhD
Laura Donlin, PhD

Hospital for Special Surgery Research Institute

Ari Molofsky, MD, PhD
Ari Molofsky, MD, PhD

University of California, San Francisco

Edna Cukierman,PhD
Edna Cukierman,PhD

Fox Chase Cancer Center

David Lagares, PhD
David Lagares, PhD

Harvard Medical School, Massachusetts General Hospital

Laura Santambrogio, MD, PhD
Laura Santambrogio, MD, PhD

Weill Cornell Medical College

Michael L. Whitfield, PhD
Michael L. Whitfield, PhD

Geisel School of Medicine at Dartmouth

Carolin K. Koss
Carolin K. Koss

Boehringer Ingelheim, University of Konstanz

Scientific Organizing Committee

Dmitry Gabrilovich, PhD

The Wistar Institute

Kang Liu, PhD

Boehringer Ingelheim

Theresa Lu, MD, PhD

Hospital for Special Surgery Research Institute

Jeanine Pignatelli, PhD

Boehringer Ingelheim

Meera Ramanujam, PhD

Boehringer Ingelheim

Sara Donnelly, PhD

The New York Academy of Sciences

Sonya Dougal, PhD

The New York Academy of Sciences


Tuesday

June 09, 2020

11:00 AM

Introduction and Welcome Remarks

Speaker

Sara Donnelly, PhD
New York Academy of Sciences

Keynote Address

11:10 AM

The Role of Stromal Cells and ECM in Chronic Inflammatory Diseases and Cancer

Speaker

Ellen Puré, PhD
University of Pennsylvania School of Veterinary Medicine

Session 1

11:55 AM

In an ECM Dependent Manner, via Nutritional Support & Immunosuppression, Cancer-Associated Fibroblasts Support Pancreatic Tumorigenesis

Speaker

Edna Cukierman, PhD
Fox Chase Cancer Center
12:25 PM

Cancer Associated Fibroblasts Support Immune Suppression by Inhibiting Dendritic Cell Maturation and Antigen Presentation

Speaker

Priya Govindaraju
Boehringer Ingelheim
12:40 PM

Collagen Scavenging Alters Macrophage Phenotype in Pancreatic Cancer

Speaker

Madeleine La Rue
New York University Langone Medical Center
12:55 PM

Break

1:05 PM

A Pathologic Macrophage-Fibroblast Circuit in Rheumatoid Arthritis

Speaker

Laura Donlin, PhD
HSS Research Institute
1:35 PM

The Anti-Fibrotic Drug Nintedanib Promotes Expansion of Lung Macrophages with a Distinct Transcriptional Repair Program in Bleomycin-Exposed Mice

Speaker

Carolin K. Koss
Boehringer Ingelheim; University of Konstanz
2:05 PM

Break

Session 2

2:35 PM

Stromal Crosstalk with Allergic Immunity at Tissue Boundaries

Speaker

Ari Molofsky, MD, PhD
UCSF
3:05 PM

Mechanisms controlling the Balance between Tissue Regeneration and Fibrosis

Speaker

David Lagares, PhD
Harvard Medical School
3:35 PM

Break

3:45 PM

Proteomic Analysis of Lymph Fluid

Speaker

Laura Santambrogio, MD, PhD
Weill Cornell Medical College
4:15 PM

Genomic and Computational Approaches to Identify the Molecular Basis of Autoimmunity and Fibrosis

Speaker

Michael L. Whitfield, PhD
Geisel School of Medicine at Dartmouth
4:45 PM

Closing Remarks

4:50 PM

Adjourn

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