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Phenotypic Drug Discovery: Leveraging Computational Tools

Phenotypic Drug Discovery: Leveraging Computational Tools

Thursday, June 4 - Friday, June 5, 2020

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York

Presented By

The Biochemical Pharmacology Discussion Group

The New York Academy of Sciences

 

Phenotypic screening has recently led to discoveries of first-in-class drugs with novel mechanisms of action. Due to this success, interest in this strategy has experienced a renaissance. In contrast to target-based strategies, phenotypic drug discovery does not rely on knowledge of a specific drug target or a hypothesis about its role in disease, but instead focuses on finding a gene or small molecule that corrects a cellular characteristic that is specific to disease. Along with this new strategy, major advances in high throughput technologies have resulted in immense phenotypic datasets. However, these recent advances in automated screening technology have resulted in a dilemma: experimental data can be generated at a much faster rate than researchers can possibly analyze and integrate them. This inefficiency makes it difficult to conduct certain types of experiments on a large scale, wastes investments, and delays the drug discovery process. This symposium will provide a snapshot of the current state of computational methods used in phenotypic screening and novel in silico approaches, and include discussions of deep learning, AI, functional genomics, chemical screening, systems biology, target deconvolution, biomarkers, and toxicity.

Call for Abstracts

Abstract submissions are invited for a poster session. For complete submission instructions, please visit our online portal. The deadline for abstract submission is Friday, March 27, 2020.

Registration

Member
By 04/24/2020
$250
After 04/24/2020
$340
Nonmember Academia, Faculty, etc.
By 04/24/2020
$400
After 04/24/2020
$540
Nonmember Corporate, Other
By 04/24/2020
$475
After 04/24/2020
$640
Nonmember Not for Profit
By 04/24/2020
$400
After 04/24/2020
$540
Nonmember Student, Undergrad, Grad, Fellow
By 04/24/2020
$270
After 04/24/2020
$365
Member Student, Post-Doc, Fellow
By 04/24/2020
$220
After 04/24/2020
$300
Earlybird Registration:
137
days
left
Deadline:
109
days
left

Keynote Speaker

Michael A White, PhD

Pfizer

Speakers

Andrea Califano, PhD

Columbia University

Yolanda Chong, PhD

Recursion Pharmaceuticals

Paul A. Clemons, PhD

Broad Institute of MIT and Harvard

Olivier Elemento, PhD

Weill Cornell Medical College

Johannes M. Freudenberg, PhD

GlaxoSmithKline

Rajarshi Guha, PhD

Vertex Pharmaceuticals

Michael Keiser, PhD

University of California, San Francisco

Elizabeth McMillan, PhD

Pfizer

Nicholas Tatonetti, PhD

Columbia University

Bridget Wagner, PhD

Broad Institute of MIT and Harvard

Scientific Organizing Committee

Kira A. Armacost, PhD

Merck

Timothy J. Cardozo, MD, PhD

New York University

Ye Che, PhD

Pfizer

Paul A. Clemons, PhD

Broad Institute of MIT and Harvard

Guanglei Cui, PhD

GlaxoSmithKline

Olivier Elemento, PhD

Weill Cornell Medical College

Adam Gilbert, PhD

Pfizer

Susan Pieniazek, PhD

Bristol-Myers Squibb

Marie-Claire Peakman, PhD

Pfizer

Marco Prunotto, PhD

Roche

Alison Carley, PhD

The New York Academy of Sciences

Sonya Dougal, PhD

The New York Academy of Sciences