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Engineering Solutions For Cardiovascular Diseases

Engineering Solutions For Cardiovascular Diseases

Monday, April 5 - Friday, April 16, 2021 EDT

Online Course

Presented By

The New York Academy of Sciences

 

Engineering Solutions For Cardiovascular Diseases
Engineering Solutions For Cardiovascular Diseases

Did you know that cardiovascular diseases are the number one cause of death around the world? Interestingly, most of these begin with the uncontrolled formation of blood clots, also known as thrombosis. Thus, in order to avoid clotting complications, it is important to understand all the factors that promote its formation. For instance, can physical factors such as blood vessel geometry, blood flow, and turbulence affect the incidence of vein thrombosis? Questions of this nature will be explored throughout this course by learning about the cardiovascular system and how scientists have devised exciting new ways to study it.

In order to further immerse ourselves into the cardiovascular research field, we will be working with the AutoCAD software in order to generate and compare computational models of healthy and diseased blood vessels. We will appreciate how our computational models can then be used for fluid dynamics simulations as well as for fabrication into actual fluidic devices used in biomedical research labs. These activities will prepare you to tackle biomedical research questions through intelligent design of your very own fluidic device. Unleash your creativity and let’s get ready to solve some cardiovascular problems!

$495/student for this two-week camp

Week 1: April 5-9

Week 2: April 12-16

Online via Zoom. Two hours of in-person teaching time with intermittent group breakout sections Monday through Friday. Students will be assigned work outside of class to be completed independently and in small groups.

Daily Monday through Friday, 4:00-6:00PM EST


Andrés Moya-Rodríguez, PhD Candidate in Biophysical Sciences at the University of Chicago, is a Biophysical Sciences graduate student at the University of Chicago interested in vascular biology, teaching and STEM outreach. He pursued his Chemistry undergraduate studies at the University of Puerto Rico where he collaborated in research projects in the realm of biochemistry, bioremediation and electrophysiology. Upon graduation, Andrés did a post-baccalaureate at Yale University where he conducted research in a virology laboratory. Throughout his academic career, he has been avidly involved in outreach initiatives and served as a research mentor to several high school and undergraduate students. Outside of science, Andrés likes animals, video games, sketching, singing and fitness.

Objectives

  • Students will familiarize themselves with the current state of the cardiovascular research field.
  • Develop proficiency in AutoCAD software to create blood vessel computational models.
  • Understand cardiovascular and biomedical engineering concepts to design fluidic devices intended for biomedical research.

Outcomes

  1. Identify thrombus and clot formation, atherosclerosis, vein occlusion as questions cardiovascular research is addressing.
  2. Demonstrate proficiency in AutoCAD by creating blood vessel computational models.
  3. Demonstrate cardiovascular and biomedical engineering concepts by designing fluidic devices.


Biomedical research approaches have evolved in order to mimic biological systems as well as possible. Especially in a vascular biology laboratory, it is important to accurately capture the blood vessel geometry before proceeding to run computational simulations and/or perform flow experiments. Thus, we will be gaining familiarity with AutoCAD software in order to appreciate its novel applications in research.

Fluidic devices are small chips that allow us to flow liquids through them at different flow rates. These devices can be designed in AutoCAD for subsequent fabrication and use. Vascular research takes advantage of these to mimic veins and arteries dimensions to better understand cardiovascular diseases in the laboratory (in vitro). In this course, we will look into the process of design and fabrication of devices for relevant research applications.

Absolutely! This course is highly interdisciplinary which means there is something for everyone. Also, the the course is meant to be introductory and aims to motivate students to come up with their own biomedical research ideas and ways to realize them.

Online sessions will meet weekdays, Monday to Friday from 4:00-6:00pm EST. Additionally, students can expect to spend between 5-10 hours outside of class on activities and projects.

Our STEM Camps are for high school students (grades 9-12) only.

The ideal student is self-motivated and eager to deepen their understanding of STEM-related subjects.

There are no prerequisites other than an interest in STEM-related subjects.

Select the camp that you are interested in and scroll down to register.

Payment is due immediately upon registration. The deadline to register is Wednesday, March 31.

The two-week camp costs $495/student.

Unfortunately, discounts and scholarships are not available at this time. We hope that this is something we can offer need-based students in the future.

All registrations and payments are final and nonrefundable. Families are not able to reschedule or transfer into a different camp, once registered, so please consider course choices carefully. The Academy has the right to cancel the camp for any reason. If for any reason the Academy, cancels or postpones camp, registered participants will have the option to receive a refund or credit.

Students will earn a certificate from the Academy for successfully completing a STEM Camp.

The courses will be delivered via Zoom. A laptop or computer (Macs &amp PC’s both ok) with access to the Internet is required. In some cases, access to mobile devices will also be required. Additional software requirements vary by camp - please see individual STEM Camp details for more information.

If you are experiencing issues for any reason, you can contact customerservice@nyas.org.

You can share feedback directly with the instructor or by emailing camps@nyas.org. Families will also be invited to complete a survey at the conclusion of the program, to provide additional feedback.

Images and Documents

Computational models of blood vessels can be fabricated through 3D printing and ultimately utilized to perform flow experiments in the laboratories. Fluorescent tracer beads are added to the flowing solution to visualize flow behavior across the fluidic device using fluorescent microscopy. 

Particle Image Velocimetry (PIV) of the flowing channel within the fluidic device can give us information about flow behavior as well as forces exerted on the channel wall. This provides insights into the forces that cells comprising blood vessels experience under different flow conditions. Ultimately, we can determine what magnitude of forces promote complications, such as thrombosis, as well as the force range that keeps blood vessels healthy.

Computational model of the cephalic vein made using engineering software such as AutoCAD and Solidworks. These models can be used to run flow simulations and better understand how blood flow affects diverse blood vessel geometries. This computational approach can help us better understand cardiovascular disease progression under customizable blood flow conditions.

Registration

Individual
$495
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