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CRISPR: New Frontiers March 2021

WEBINAR

Only

CRISPR: New Frontiers March 2021

Monday, March 15, 2021, 10:45 AM - 2:15 PM EDT

Webinar

Presented By

CRISPR Discussion Group

The New York Academy of Sciences

 

The discovery of CRISPR–Cas systems and their development for gene-editing applications have revolutionized biomedical science. These systems are pervasive within the genomes of bacteria and archaea, where they provide adaptive immunity by targeting foreign nucleic acids for degradation. An incredibly diverse and rapidly growing set of CRISPR systems have been identified, and recent work harnessing them to target and modify specific RNA and DNA sequences has enabled a multitude of applications, such as genome editing, transcriptional modulation, forward genetic screens, lineage tracing, and more.

The CRISPR: New Frontiers meeting will bring together researchers uncovering the cellular, molecular, and biochemical pathways of CRISPR-associated proteins, DNA repair pathways, and applications in diverse organisms, including for human health and disease biology.

Call for Abstracts

Deadline February 22, 2021

Abstracts are invited for consideration for short talks. To submit an abstract, please visit our online portal. See here for submission guidelines. The deadline for abstract submission is February 22, 2021.


Academy Members save 50% or more on event registration. Not a Member? Join today. Students and postdocs may be eligible for Membership through the Science Alliance program. To find out if your school is a Science Alliance partner, click here.

Registration

Member
$5
Nonmember Academia, Faculty, etc.
$30
Nonmember Corporate, Other
$45
Nonmember Not for Profit
$30
Nonmember Student, Undergrad, Grad, Fellow
$10
Member Student, Post-Doc, Fellow
$0

Organizing Committee

Britt Adamson, PhD
Britt Adamson, PhD

Princeton University

Maria Jasin, PhD
Maria Jasin, PhD

Memorial Sloan Kettering Cancer Center

Neville Sanjana, PhD
Neville Sanjana, PhD

New York Genome Center and New York University

Samuel Sternberg, PhD
Samuel Sternberg, PhD

Columbia University

Alison Carley, PhD
Alison Carley, PhD

New York Academy of Sciences

Keynote Speaker

J. Keith Joung, MD, PhD
J. Keith Joung, MD, PhD

Harvard Medical School and Massachusetts General Hospital

Speakers

Alberto Ciccia
Alberto Ciccia, PhD

Columbia University Irving Medical Center

Dieter Elgi
Dieter Egli, PhD

Columbia University Irving Medical Center

Nicole Gaudelli, PhD
Nicole Gaudelli, PhD

Beam Therapeutics

Elani Mimitou​
Eleni Mimitou, PhD

New York Genome Center

Lukas Dow, PhD
Lukas Dow, PhD

Weill Cornell Medicine

Isabel Weisheit, MSc
Isabel Weisheit, MSc

Institute for Stroke and Dementia Research, University Hospital, LMU Munich

Monday

March 15, 2021

10:50 AM

Welcome Remarks

Speaker

Alison Carley, PhD
New York Academy of Sciences
11:00 AM

Keynote Lecture: Impacts of human genetic diversity and variation on CRISPR gene editor off-targets

Speaker

J. Keith Joung, MD, PhD
Harvard Medical School and Massachusetts General Hospital
11:45 AM

An adenine base editing strategy for the treatment of sickle cell disease by elimination of the pathogenic globin protein

Speaker

Nicole Gaudelli, PhD
Beam Therapeutics
12:15 PM

Reconstructing the cancer genome through base editing

Speaker

Lukas Dow, PhD
Weill Cornell Medicine
12:30 PM

Break

12:45 PM

Detection of Deleterious On-Target Effects after HDR-Mediated CRISPR Editing

Speaker

Isabel Weisheit, MSc
Institute for Stroke and Dementia Research, University Hospital, LMU Munich
1:00 PM

Heritable genome editing — opportunities and challenges in research and clinical translation

Speaker

Dieter Egli, PhD
Columbia University Irving Medical Center
1:30 PM

Functional interrogation of nucleotide variants of the DNA damage response with base editing screens

Speaker

Alberto Ciccia, PhD
Columbia University Irving Medical Center
2:00 PM

Highly multimodal measurements of single cells

Speaker

Eleni Mimitou, PhD
New York Genome Center
2:30 PM

Adjourn