CRISPR Discussion Group
The discovery of CRISPR–Cas systems and their development for gene-editing applications have revolutionized biomedical science. These systems are pervasive within the genomes of bacteria and archaea, where they provide adaptive immunity by targeting foreign nucleic acids for degradation. An incredibly diverse and rapidly growing set of CRISPR systems have been identified, and recent work harnessing them to target and modify specific RNA and DNA sequences has enabled a multitude of applications, such as genome editing, transcriptional modulation, forward genetic screens, lineage tracing, and more.
The CRISPR Discussion Group will advance our understanding of the cellular, molecular, and biochemical pathways of CRISPR-associated proteins, DNA repair pathways, and their applications in diverse organisms, including for human health and disease biology.
Sonya Dougal, PhD
Steering Committee Members
The CRISPR Discussion Group Steering Committee, composed of multi-institutional scientists from the Academy’s network, provides thought leadership on key issues of interest to the CRISPR community, informing and shaping our program portfolio.
Memorial Sloan Kettering Cancer Center
New York University and New York Genome Center