The disciplines of neuroscience and immunology have made substantial scientific achievements, yet the two rarely find a common language and purpose necessary to support scientific breakthroughs. Coming from the study of a variety of seemingly disparate diseases, elements that were previously considered to be domains of one discipline are now discovered in the other (for example, synapses made by T-cells, and cytokines as neuromodulators).
This symposium provides an introduction to the interdisciplinary field of neuroimmunology and presents a compelling case for the role of specific inflammatory cytokines in sickness behavior and clinical depression. Additional topics include how cytokines mediate the stress response at molecular, cellular and systems levels, the molecular mechanisms of cellular stress in Alzheimer's disease and how proinflammatory signaling plays a role in amyloid-beta peptide mediated neuronal dysfunction and memory impairment. Research will be presented that identifies the neurotoxic mechanisms and transduction pathways that are associated with TNFa signaling and potential therapeutic strategies for neurodegenerative diseases via modulating glial reactivity and inflammatory cytokines, and recent discoveries will be unveiled on specific receptors for fibrinogen that advance our understanding of its role from clotting factor to regulator of inflammation.
This event will also be broadcast as a webinar
Transmission of presentations via the webinar is subject to individual consent by the speakers. Therefore, we cannot guarantee that every speaker's presentation will be broadcast in full via the webinar. To access all speakers' presentations in full, we invite you to attend the live event in New York City where possible.