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  • Neuroscience and Immunology: Intersection Yields Clues for the Etiology of Psychiatric and Neurodegenerative Diseases

    Tuesday, October 26, 2010 | 1:00 PM - 5:00 PM
    The New York Academy of Sciences

    Presented by the Biochemical Pharmacology Discussion Group and the New York Chapter of the American Chemical Society

    The disciplines of neuroscience and immunology have made substantial scientific achievements, yet the two rarely find a common language and purpose necessary to support scientific breakthroughs. Coming from the study of a variety of seemingly disparate diseases, elements that were previously considered to be domains of one discipline are now discovered in the other (for example, synapses made by T-cells, and cytokines as neuromodulators).

    This symposium provides an introduction to the interdisciplinary field of neuroimmunology and presents a compelling case for the role of specific inflammatory cytokines in sickness behavior and clinical depression. Additional topics include how cytokines mediate the stress response at molecular, cellular and systems levels, the molecular mechanisms of cellular stress in Alzheimer's disease and how proinflammatory signaling plays a role in amyloid-beta peptide mediated neuronal dysfunction and memory impairment. Research will be presented that identifies the neurotoxic mechanisms and transduction pathways that are associated with TNFa signaling and potential therapeutic strategies for neurodegenerative diseases via modulating glial reactivity and inflammatory cytokines, and recent discoveries will be unveiled on specific receptors for fibrinogen that advance our understanding of its role from clotting factor to regulator of inflammation.

    Organizers

    Seongeun (Julia) Cho, PhD

    Food and Drug Administration

    Ken Jones, PhD

    Lundbeck Research USA

    Lars Pedersen, PhD

    Lundbeck

    Jennifer Henry, PhD

    The New York Academy of Sciences

    Speakers

    Katerina Akassoglou, PhD

    Gladstone Institute & UCSF

    Andrew Miller, MD

    Emory University School of Medicine

    Malú Tansey, PhD

    Emory University School of Medicine 

    Shi Du Yan, MD, MS

    Columbia University

    Raz Yirmiya, PhD

    Hebrew University
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