The emergence of carbapenem resistant Enterobacteriaceae in the New York metropolitan area has foreshadowed the global spread of these highly resistant Gram negative pathogens. Carbapenem-resistant K. pneumoniae (KPC strains) are recovered routinely in many hospitals in New York City and New Jersey where they have caused high rates of morbidity and mortality, particularly among the critically ill. A similar story is emerging from the India, where resistant K. pneumoniae harboring NDM-1 resistance has been described in contaminated water in the community. The epidemiological and clinical dilemma is related to the fact that both KPC and NDM resistance is mediated on mobile plasmids that are able to spread among species with the Enterobacteriaceae family and that treatment is now limited to combinations with colistin, tigecycline, and rifampin, and resistance to all these agents has been reported. This symposium, organized in conjunction with the Public Health Research Institute, UMDNJ–NJMS, will discuss the issues surrounding the molecular epidemiology of carbapenem resistant Enterobacteriaceae, the complexity of their multidrug resistance, and the clinical challenges in both diagnosing resistance and treating immunocompromised patients.
Networking reception to follow.
|Student / Postdoc / Fellow Member
|Student / Postdoc / Fellow Nonmember