• Cognitive Dysfunction in Multiple Sclerosis

    New Approaches to Diagnosis and Treatment

    Cognitive Dysfunction in Multiple Sclerosis

    New Approaches to Diagnosis and Treatment

    Keynote Speaker: Aaron E. Miller (Mount Sinai School of Medicine)
    Organizer: Sonya Dougal, PhD (The New York Academy of Sciences)
    Presented by the New York Academy of Sciences
    Reported by Sarah Webb | Posted August 25, 2011


    Multiple sclerosis (MS) is a degenerative autoimmune disorder that affects the transfer of neural impulses. The immune system destroys the fatty myelin sheath that insulates axons in the central nervous system, the brain, and the optical system, causing signals in these areas to travel less efficiently. As a result, patients usually have problems with movement and vision and have, in up to 70 % of cases, some degree of cognitive impairment.

    Although there is no cure for MS, treatments are available to delay and to manage many of the physical symptoms. Cognitive impairments are highly variable, hard to assess, and therefore difficult to treat. During this meeting, Cognitive Dysfunction in Multiple Sclerosis: New Approaches to Diagnosis and Treatment, held from June 21 – 23, 2011 at the New York Academy of Sciences, neurologists, neurobiologists, neuropsychologists, genomics and imaging experts, and patient advocates gathered to discuss cognitive impairments in MS. Over the course of this 2.5 day meeting, researchers discussed the neurobiological underpinnings of cognitive impairment in MS, drug therapies that can improve cognition, tests for diagnosing cognitive impairment in MS, and brain imaging studies to better understand cognitive dysfunction.

    Use the tabs above to find a meeting report and multimedia from this event.


    Presentations available from:

    Peter Arnett, PhD (Penn State University)
    Jacqueline T. Bernard, MD (University of Chicago)
    Peter Calabresi, MD (Johns Hopkins University School of Medicine)
    Patrizia Casaccia, MD, PhD (Mount Sinai School of Medicine)
    John DeLuca, PhD (Kessler Foundation Research Center)
    Ranjan Dutta, PhD (The Cleveland Clinic)
    Massimo Filippi, MD (University San Raffaele, Milan, Italy)
    Robert L. Kane, PhD (Washington Neuropsychology Research Group)
    Lauren Krupp, PhD (Stony Brook University Medical Center)
    Aaron E. Miller, MD (Mount Sinai School of Medicine)
    Daniel Pelletier, MD (Yale University School of Medicine)
    Stephen M. Rao, PhD (Cleveland Clinic Foundation)
    Daniel Reich, MD, PhD (National Institute of Neurological Disorders and Stroke)
    Nancy Sicotte, MD (Cedars-Sinai Medical Center)
    Stephen G. Waxman, MD, PhD (Yale University School of Medicine and Veterans Affairs Connecticut)
    Heather Wishart, PhD (Dartmouth Medical School)
    Patient Advocacy Panel Discussion

    Presented by

    • The New York Academy of Sciences

    Gold Sponsors

    • Biogen Idec
    • Elan

    Grant Support

    Acorda Therapeutics

    Bayer HealthCare


    Academy Friend

    National Multiple Sclerosis Society