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Frontiers in Cancer Immunotherapy

Available via

WEBINAR

Frontiers in Cancer Immunotherapy

Tuesday, May 14, 2019, 8:00 AM - Wednesday, May 15, 2019, 5:30 PM EDT

The New York Academy of Sciences, 7 World Trade Center, 250 Greenwich St Fl 40, New York

Presented By

Cancer Discussion Group

The New York Academy of Sciences

 

Immuno-oncology promises a revolution in the way we treat cancer. Since the approval of the first checkpoint inhibitors in 2014, and the subsequent approval of the first cellular therapy in 2017, the field of cancer immunotherapy has exploded with numerous ongoing clinical trials. Despite great successes, emerging results suggest that monotherapies are not sufficient to treat many cancer types and it is increasingly clear that combinatorial approaches are needed to target heterogeneous tumors and improve variability in patient response.

This two-day symposium will convene leading experts in cancer immunotherapy to discuss cutting-edge findings in the broad area of combination therapies, including checkpoint inhibitors and cellular therapies. Particular emphasis will be given to the biological mechanisms underlying combination hypotheses, bispecific antibodies and other emerging modalities for delivery of combination therapies, as well as a discussion of the importance of biomarkers and effective clinical trial design.

Registration

Member
By 04/02/2019
$250
After 04/02/2019
$340
Nonmember Academia, Faculty, etc.
By 04/02/2019
$400
After 04/02/2019
$540
Nonmember Corporate, Other
By 04/02/2019
$475
After 04/02/2019
$640
Nonmember Not for Profit
By 04/02/2019
$400
After 04/02/2019
$540
Nonmember Student, Undergrad, Grad, Fellow
By 04/02/2019
$270
After 04/02/2019
$365
Member Student, Post-Doc, Fellow
By 04/02/2019
$220
After 04/02/2019
$300
Member
$30
Nonmember Academia, Faculty, etc.
$65
Nonmember Corporate, Other
$85
Nonmember Not for Profit
$65
Nonmember Student, Undergrad, Grad, Fellow
$45
Member Student, Post-Doc, Fellow
$15
Member
$30
Nonmember Academia, Faculty, etc.
$65
Nonmember Corporate, Other
$85
Nonmember Not for Profit
$65
Nonmember Student, Undergrad, Grad, Fellow
$45
Member Student, Post-Doc, Fellow
$15
Member
$60
Nonmember Academia, Faculty, etc.
$130
Nonmember Corporate, Other
$170
Nonmember Not for Profit
$130
Nonmember Student, Undergrad, Grad, Fellow
$90
Member Student, Post-Doc, Fellow
$30
Deadline:
0
days
left

Scientific Organizing Committee

Chris Boshoff, MD, PhD,  Pfizer
Chris Boshoff, MD, PhD,
Pfizer
Renier Brentjens, MD, PhD,  Memorial Sloan Kettering Cancer Center
Renier Brentjens, MD, PhD,
Memorial Sloan Kettering Cancer Center
Sridhar Ramaswamy, MD,   Tesaro
Sridhar Ramaswamy, MD,
Tesaro
George Zavoico, PhD,  B. Riley FBR
George Zavoico, PhD,
B. Riley FBR
Sara Donnelly, PhD, The New York Academy of Sciences
Sara Donnelly, PhD, The New York Academy of Sciences
Sonya Dougal, PhD, The New York Academy of Sciences
Sonya Dougal, PhD, The New York Academy of Sciences

Keynote Speaker

James P. Allison, PhD,  MD Anderson Cancer Center
James P. Allison, PhD,
MD Anderson Cancer Center

Speakers

Thomas Gajewski, MD, PhD,  The University of Chicago
Thomas Gajewski, MD, PhD,
The University of Chicago
Jedd Wolchok, MD, PhD,
Jedd Wolchok, MD, PhD,

Memorial Sloan Kettering Cancer Center

Padmanee Sharma, MD, PhD,  MD Anderson Cancer Center
Padmanee Sharma, MD, PhD,
MD Anderson Cancer Center
Philip D. Greenberg, MD
Philip D. Greenberg, MD

Fred Hutchinson Cancer Research Center

Ronald Levy, MD,  Stanford University School of Medicine
Ronald Levy, MD,
Stanford University School of Medicine
Lisa H. Butterfield, PhD,
Lisa H. Butterfield, PhD,

Parker Institute for Cancer Immunotherapy

Donald A. Berry, PhD
Donald A. Berry, PhD

MD Anderson Cancer Center

Rachel W. Humphrey, MD,  CytomX Therapeutics
Rachel W. Humphrey, MD,
CytomX Therapeutics
James Yang, MD
James Yang, MD

National Cancer Institute

Judith Varner, PhD,  University of California, San Diego School of Medicine
Judith Varner, PhD,
University of California, San Diego School of Medicine
Jane L. Grogan, PhD  Genentech
Jane L. Grogan, PhD
Genentech
Kristen Hege, MD  Celgene
Kristen Hege, MD
Celgene
Maria Fardis, PhD, MBA
Maria Fardis, PhD, MBA

Iovance Biotherapeutics

Silvia C. Formenti, MD,  Weill Cornell Medical College
Silvia C. Formenti, MD,
Weill Cornell Medical College
Frederic Triebel
Frederic Triebel, MD, PhD

Immutep

Anish Suri, PhD
Anish Suri, PhD

Cue Biopharma

Laurent Levy, PhD
Laurent Levy, PhD

Nanobiotix

Renier Brentjens, MD, PhD
Renier Brentjens, MD, PhD

Memorial Sloan Kettering Cancer Center

Amit Kumar, PhD
Amit Kumar, PhD

Anixa Biosciences

Maya Kotturi, PhD
Maya Kotturi, PhD

Compugen

Jean Albrengues, PhD
Jean Albrengues, PhD

Cold Spring Harbor Laboratory

Adnan A. Jaigirdar, MD, FACS
Adnan A. Jaigirdar, MD, FACS

US Food and Drug Administration

Samit Hirawat, MD, PhD
Samit Hirawat, MD, PhD

Novartis

Event Sponsors






Tuesday

May 14, 2019

8:00 AM

Breakfast and Registration

9:00 AM

Introduction and Welcome Remarks

Speakers

Sonya Dougal, PhD
The New York Academy of Sciences
Chris Boshoff, MD, PhD
Pfizer

Session 1

Session Chairperson
Chris Boshoff, MD, PhD, Pfizer
9:15 AM

Immune Checkpoint Blockade: Blurring the Line between Autoimmunity and Tumor Immunity

Speaker

Jedd Wolchok, MD, PhD
Memorial Sloan Kettering Cancer Center
10:00 AM

From the Clinic to the Lab: Investigating Response and Resistance Mechanisms to Immune Checkpoint Therapy

Speaker

Padmanee Sharma, MD, PhD
MD Anderson Cancer Center
10:30 AM

Panel Discussion: Innovative Approaches in Clinical Trial Design

Speakers

Jedd Wolchok, MD, PhD (moderator)
Memorial Sloan Kettering Cancer Center
Donald A Berry, PhD
MD Anderson Cancer Center
Adnan Jaigirdar, MD, FACS
Food and Drug Administration
Samit Hirawat, MD
Novartis
Padmanee Sharma, MD, PhD
MD Anderson Cancer Center
11:15 AM

Networking Coffee Break

11:45 AM

Epigenetic Regulation of Tumor-Associated Myeloid Cells

Speaker

Jane Grogan, PhD
Genentech
12:15 PM

BCMA Targeted Immunotherapy for Multiple Myeloma

Speaker

Kristen Hege, MD
Celgene
12:45 PM

Networking Lunch and Poster Session

Speaker

Even Numbered Posters: 1:15 PM - 2:00 PM

Session 2

Session Chairperson
George Zavoico, PhD, B. Riley FBR
2:00 PM

Tumor Antigens and the Immune System

Speaker

Lisa H. Butterfield, PhD
The Parker Institute for Cancer Immunotherapy
2:45 PM

PD-L1 Probody Therapeutics

Speaker

Rachel Humphrey, MD
CytomX
3:15 PM

Networking Coffee Break

3:45 PM

Targeting Tumors with T Cells Engineered to Overcome Therapeutic Obstacles

Speaker

Philip Greenberg, MD
Fred Hutchinson Cancer Research Center
4:30 PM

Day 1 Wrap Remarks

Speaker

George Zavoico, PhD
B. Riley FBR
4:35 PM

Networking Reception and Poster Session

Speaker

Odd Numbered Posters: 4:45 PM - 5:30 PM
5:30 PM

Day 1 Adjourns

Wednesday

May 15, 2019

8:00 AM

Breakfast and Registration

8:00 AM

Career Development Breakfast for Graduate Students and Post-docs

9:00 AM

Welcome Remarks

Speaker

Sara Donnelly, PhD
The New York Academy of Sciences

Session 3

Session Chairperson
Rachel Humphrey, MD, CytomX
9:15 AM

In Situ Vaccination for Cancer

Speaker

Ronald Levy, MD
Stanford University
10:00 AM

Microbiota and Anti-Tumor Immunity

Speaker

Thomas Gajewski, MD, PhD
University of Chicago
10:30 AM

Networking Coffee Break

11:00 AM

Radiation in Combination with Checkpoint Inhibitors

Speaker

Silvia C. Formenti, MD
Weill Cornell Medical College
11:30 AM

Data Blitz - Role of Notch Signaling on Human Dendritic Cell Subset Differentiation

Speaker

Sreekumar Balan, PhD
Icahn School of Medicine at Mount Sinai
11:35 AM

Data Blitz - Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells

Speaker

Yuxuan Miao, PhD
The Rockefeller University
11:40 AM

Data Blitz - Induction of the Senescence-Associated Secretory Phenotype Makes “Cold” Pancreas Tumors “Hot” and Potentiates PD-1 Blockade Immunotherapy

Speaker

Marcus Ruscetti, PhD
Memorial Sloan Kettering Cancer Center
11:45 AM

Networking Lunch

Session 4: Breakout Track A**

Session Chairperson
George Zavoico, PhD, B. Riley FBR (**this session will not be part of the webinar)
1:00 PM

Novel Approaches from Biotech

Speakers

Anish Suri, PhD
Cue Biopharma
Frederic Triebel, MD, PhD
Immutep Ltd.
Laurent Levy, PhD
Nanobiotix
Maya Kotturi, PhD
Compugen

Session 4: Breakout Track B

Session Chairperson
Chris Boshoff, MD, PhD, Pfizer
1:00 PM

Targeting Solid Tumors with Immunotherapy

Speakers

Renier Brentjens, MD, PhD
Memorial Sloan Kettering Cancer Center
Amit Kumar, PhD
Anixa Biosciences
Maria Fardis, PhD, MBA
Iovance Biotherapeutics

Session 5

2:00 PM

Targeting Macrophage Mediated Immune Suppression to Promote Effective Cancer Immune Therapy

Speaker

Judith Varner, PhD
University of California San Diego School of Medicine
2:30 PM

Neutrophil Extracellular Traps Produced During Inflammation Awaken Dormant Cancer Cells

Speaker

Jean Albrengues, PhD
Cold Spring Harbor Laboratory
3:00 PM

Networking Coffee Break

3:30 PM

Cellular Immunotherapy for Common Epithelial Cancers

Speaker

James Yang, MD
National Cancer Institute
4:00 PM

Keynote ~ Immune Checkpoint Blockade in Cancer Therapy: Historical Perspective, New Opportunities

Speaker

James Allison, PhD
MD Anderson Cancer Center
4:45 PM

Closing Remarks

Speaker

Renier Brentjens, MD, PhD
Memorial Sloan Kettering Cancer Center
5:00 PM

Conference Adjourns