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  • Annals of the New York Academy of Sciences

  • Annals

    Pepducin symposium explores a new approach to GPCR modulation

    This special Annals meeting report covers new work in the field of pepducins: lipopeptides that modulate heptahelical G-protein coupled receptor activity from inside the cell membrane.

  • Recent Annals 

    November 2009

    Pepducin symposium explores a new approach to GPCR modulation

    Jacquelyn Miller (MacDougall Biomedical Communications, Wellesley, Massachusetts), Anika Agarwal and Athan Kuliopulos (Tufts Medical Center, Boston, Massachusetts), Lakshmi A. Devi (Mount Sinai School of Medicine, New York, New York), Kellen Fontanini and James A. Hamilton (Boston University School of Medicine, Boston, Massachusetts), Jean-Philippe Pin (University of Montpellier, Montpellier, France), Denis C. Shields (The University College of Dublin, Dublin, Ireland), C. Arnold Spek (University of Amsterdam, Amsterdam, the Netherlands), Thomas P. Sakmar (The Rockefeller University, New York, New York), and Stephen W. Hunt III (Ascent Therapeutics, Cambridge, Massachusetts).

    The inaugural Pepducin Science Symposium in Cambridge, Massachusetts on March 8–9, 2009 provided the opportunity for an international group of scientists to present and discuss how pepducins modulate G protein–coupled receptor-related research.

    Free online meeting report

    November 2009

    Biomarkers in Brain Disease

    Edited by Simon Lovestone (King's College, University of London)

    Experts discuss the latest advances in biomarker technologies and biomarker development for brain disorders, and the logistical, regulatory, and funding challenges experienced by scientists working on clinical trials for biomarkers.

    November 2009

    Glucocorticoids and Mood: Clinical Manifestations, Risk Factors, and Molecular Mechanisms

    Edited by Lewis L. Judd (Department of Psychiatry, University of California, San Diego) and Esther Sternberg (Integrative Neural Immune Program, Section on Neuroendocrine Immunology and Behavior, NIMH, NIH, Bethesda, Maryland)

    New basic research provides important insights into possible mechanisms of action that promote negative sequelae in vulnerable and susceptible patients who receive glucocorticoid treatment.

    October 2009

    Hypoxia and Consequences: From Molecule to Malady

    Edited by Chris Peers (School of Medicine, University of Leeds, Leeds, UK), Gabriel G. Haddad (University of California, San Diego, California), and Navdeep S. Chandel (Northwestern University, Evanston, Illinois)

    This volume explores the transcriptional and pathophysiological responses to hypoxia and of the sensing mechanisms responsible for detection of oxygen level changes in the body.

    October 2009

    Natural Genetic Engineering and Natural Genome Editing

    Edited by Günther Witzany (Telos-Philosophische Praxis, Bürmoos, Austria)

    Scientists working on genome organization, genome restructuring, genome formatting, and virus research discuss how to integrate these discoveries into the basic understanding of evolution, development, and disease.

    September 2009

    Hematopoietic Stem Cells VII

    Edited by Lothar Kanz and Katja C. Weisel (University of Tübingen, Tübingen, Germany), John E. Dick (University of Toronto, Toronto, Ontario, Canada), and Willem E. Fibbe (Leiden University Medical Center, Leiden, The Netherlands)

    A fundamental property of hematopoetic stem cells is the capacity to self-renew; this volume presents recent developments and clinical implications in hematopoietic stem cell research.

    September 2009

    Oligonucleotide Therapeutics: 4th Annual Meeting

    Edited by John Rossi (Beckman Research Institute of the City of Hope, Duarte, California), Michael Gait (Medical Research Council, Cambridge, UK), and Fritz Eckstein (Max-Planck Institute for Experimental Medicine, Göttingen, Germany)

    Basic researchers in molecular biology, cell biology, nucleic acid chemistry, pharmacology, and applied therapeutics present new technologies in the field of oligonucleotide research.

    September 2009

    Cancer Vaccines: 6th International Symposium

    Edited by Ralph Steinman (The Rockefeller University, New York, New York), Jacques Banchereau (Baylor Institute for Immunology Research, Dallas, Texas), and Olivera J. Finn (School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania)

    From world-renowned researchers and clinicians, manuscripts in this volume shed light on recent steps forward in immunotherapeutic and preventive approaches for future cancer vaccines.

    September 2009

    Immunology and Pathogenesis of Viral Hemorrhagic Fevers

    Edited by Aftab Ansari, Abdul Jabbar, Tristram Parslow, and Rafi Ahmed (Emory University, Atlanta, GA)

    Leaders in the field cover basic biology, pathogenesis, epidemiology and immunology of pathogenic hemorrhagic fever arenaviruses such as dengue virus, Rift Valley fever virus, Pichinde virus, and hantavirus.

    Special online volume with free access to all articles

    September 2009

    Integrative Physiology

    Edited by Gerard Karsenty (Columbia University, New York, New York)

    Contributions from top researchers summarize the state of the art in the field of integrative physiology and speculate on how the field might move forward.

    Special online volume