• Circadian Disruption and Cancer

    Making the Connection

    Circadian Disruption and Cancer

    Making the Connection

    Keynote Speaker: Russell J. Reiter (The University of Texas Health Science Center)Jointly sponsored by the New York Academy of Sciences and the Mushett Family Foundation
    Reported by Megan Stephan | Posted August 24, 2009


    The sharp delineation between day and night present through most of evolutionary history has been eroded in industrialized societies. Increasing nocturnal light and overnight shift work has coincided with a steady increase in incidence of cancer, prompting epidemiologists and other scientists to ask if there is a connection.

    On June 19, 2009, researchers studying circadian rhythms and the physiological, biochemical, and molecular mechanisms behind them gathered at the New York Academy of Sciences to ponder this question and its implications for human health. Talks focused on three main areas: 1) evidence for the possible link between nighttime light and cancer risk, including the role of the hormone melatonin, which is the primary link between light perceived by the eyes and the internal circadian clock; 2) the molecular components of the circadian clock, and how they might interact with the pathways involved in cancer to promote or prevent it; and 3) how the development of cancer disrupts circadian rhythms in humans, and whether mitigation of this disruption could lead to better cancer treatment and outcomes.

    The symposium was organized by William Hrushevsky of the University of South Carolina and David Blask of Tulane University School of Medicine.

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    Russel J. Reiter

    Keynote Address: Cancer, Circadian Disruption, Melatonin and the Clock

    Russel J. Reiter (The University of Texas Health Science Center)

    Use the tabs above to find a meeting report and multimedia on this event.

    Speakers include:

    Georg A. Bjarnason (Sunnybrook Odette Cancer Center) *
    David E. Blask (Tulane University School of Medicine) *
    Keith I. Block (Block Center for Integrative Cancer Treatment)
    George C. Brainard (Jefferson Medical College)
    Elisabeth Filipski (French Institute of Health and Medical Research) *
    Steven M. Hill (Tulane Cancer Center) *
    William J.M. Hrushesky (University of South Carolina School of Medicine) *
    H. Phillip Koeffler (University of California, Los Angeles) *
    Steven W. Lockley (Harvard Medical School) *
    Russel J. Reiter (The University of Texas Health Science Center) *
    Tyvin A. Rich (University of Virginia) *
    Eva S. Schernhammer (Harvard Medical School) *
    Richard Stevens (University of Connecticut Health Center) *
    Patricia A. Wood (University of South Carolina) *
    Xiaoming Yang (University of South Carolina) *

    * Multimedia available


    This conference has been made possible through the generous support of the Mushett Family Foundation. Click the sponsorship tab for a complete list of sponsors.